[HTML][HTML] TMEM proteins in cancer: a review
K Schmit, C Michiels - Frontiers in pharmacology, 2018 - frontiersin.org
A transmembrane protein (TMEM) is a type of protein that spans biological membranes.
Many of them extend through the lipid bilayer of the plasma membrane but others are …
Many of them extend through the lipid bilayer of the plasma membrane but others are …
[HTML][HTML] DNA methylation in lung cancer patients: Opening a" window of life" under precision medicine
DNA methylation is a work of adding a methyl group to the 5th carbon atom of cytosine in
DNA sequence under the catalysis of DNA methyltransferase (DNMT) to produce 5-methyl …
DNA sequence under the catalysis of DNA methyltransferase (DNMT) to produce 5-methyl …
[HTML][HTML] DNA methylation in lung cancer: mechanisms and associations with histological subtypes, molecular alterations, and major epidemiological factors
PH Hoang, MT Landi - Cancers, 2022 - mdpi.com
Simple Summary Aberrant DNA methylation is associated with multiple malignancies,
including lung cancer. Differences in methylation patterns have been observed across lung …
including lung cancer. Differences in methylation patterns have been observed across lung …
TMEM196 inhibits lung cancer metastasis by regulating the Wnt/β-catenin signaling pathway
J Chen, D Wang, H Chen, J Gu, X Jiang, F Han… - Journal of Cancer …, 2023 - Springer
Purpose The TMEM196 protein, which comprises four membrane-spanning domains,
belongs to the TMEM protein family. TMEM196 was identified as a candidate tumor …
belongs to the TMEM protein family. TMEM196 was identified as a candidate tumor …
[PDF][PDF] Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation
Changes in DNA methylation are associated with normal cardiogenesis, whereas altered
methylation patterns can occur in congenital heart disease. Ten-eleven translocation (TET) …
methylation patterns can occur in congenital heart disease. Ten-eleven translocation (TET) …
[HTML][HTML] TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway
X Zhang, Y He, Y Jiang, Y Bao, Q Chen… - Oncology …, 2021 - spandidos-publications.com
Abstract Transmembrane protein 229A (TMEM229A) is a member of the TMEM family that
plays an important role in tooth differentiation and development. However, the expression …
plays an important role in tooth differentiation and development. However, the expression …
TMEM88 exhibits an antiproliferative and anti‐invasive effect in bladder cancer by downregulating Wnt/β‐catenin signaling
X Zhao, G Li, T Chong, L Xue, Q Luo… - … of Biochemical and …, 2021 - Wiley Online Library
Abstract Transmembrane protein 88 (TMEM88) acts as a novel tumor‐associated protein.
The dysregulation of TMEM88 has been observed in several tumor types. However, the …
The dysregulation of TMEM88 has been observed in several tumor types. However, the …
DNA and histone modifications as potent diagnostic and therapeutic targets to advance non-small cell lung cancer management from the perspective of 3P medicine
G Zhang, Z Wang, P Song, X Zhan - EPMA Journal, 2022 - Springer
Lung cancer has a very high mortality in females and males. Most (~ 85%) of lung cancers
are non-small cell lung cancers (NSCLC). When lung cancer is diagnosed, most of them …
are non-small cell lung cancers (NSCLC). When lung cancer is diagnosed, most of them …
[HTML][HTML] Prospects and feasibility of synergistic therapy with radiotherapy, immunotherapy, and DNA methyltransferase inhibitors in non-small cell lung cancer
C Jie, R Li, Y Cheng, Z Wang, Q Wu, C Xie - Frontiers in Immunology, 2023 - frontiersin.org
The morbidity and mortality of lung cancer are increasing, seriously threatening human
health and life. Non-small cell lung cancer (NSCLC) has an insidious onset and is not easy …
health and life. Non-small cell lung cancer (NSCLC) has an insidious onset and is not easy …
[HTML][HTML] A prognostic model based on nine DNA methylation-driven genes predicts overall survival for colorectal cancer
Z Feng, Z Liu, K Peng, W Wu - Frontiers in Genetics, 2022 - frontiersin.org
Background: Colorectal cancer (CRC) is the third most frequently diagnosed malignancy
and the fourth leading cause of cancer-related death among common tumors in the world …
and the fourth leading cause of cancer-related death among common tumors in the world …