Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice

R Jia, F Yang, P Yan, L Ma, L Yang, L Li - Free Radical Biology and …, 2021 - Elsevier
Background Clinical studies indicate that vitamin D receptor (VDR) expression is reduced in
primary biliary cirrhosis patient livers. However, the mechanism by which activated VDR …

Vitamin D status in Hashimoto's thyroiditis and its association with vitamin D receptor genetic variants

HWZ Hanna, C Rizzo, RMA Halim… - The Journal of Steroid …, 2021 - Elsevier
Background Hashimoto's thyroiditis (HT) is considered the predominant cause of
hypothyroidism in iodine sufficient countries. The deficiency of 25− OH-vitamin D3 serum …

[HTML][HTML] Apa-I polymorphism in VDR gene is related to metabolic syndrome in polycystic ovary syndrome: a cross-sectional study

BR Santos, SB Lecke, PM Spritzer - Reproductive Biology and …, 2018 - Springer
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder
determined by polygenic traits as well as environmental factors. Lower vitamin D levels have …

[HTML][HTML] Antiproliferative activity of non-calcemic vitamin D analogs on human melanoma lines in relation to VDR and PDIA3 receptors

T Wasiewicz, A Piotrowska, J Wierzbicka… - International journal of …, 2018 - mdpi.com
Vitamin D is a precursor for secosteroidal hormones, which demonstrate pleiotropic
biological activities, including the regulation of growth and the differentiation of normal and …

Positive correlation between vitamin D receptor gene FokI polymorphism and colorectal cancer susceptibility in South‐Khorasan of Iran

M Moossavi, N Parsamanesh… - Journal of cellular …, 2018 - Wiley Online Library
Colorectal cancer (CRC) is a global public health problem. Despite the major milestone in
early diagnosis and treatment of colorectal cancer, the prevalence of CRC rates is still rising …

[HTML][HTML] BsmI (rs1544410) and FokI (rs2228570) vitamin D receptor polymorphisms, smoking, and body mass index as risk factors of cutaneous malignant melanoma …

S Cauci, V Maione, C Buligan, M Linussio… - Cancer Biology & …, 2017 - ncbi.nlm.nih.gov
Objective: To investigate whether vitamin D receptor gene (VDR) BsmI-rs1544410 and FokI-
rs2228570 polymorphisms, smoking duration, and body mass index (BMI) are risk factors for …

[HTML][HTML] Evaluation of ApaI and FokI polymorphism of VDR gene and functional characterization in patients with fibromyalgia

SKFS Santos, KBP Fernandes, CAM Zicarelli… - Fisioterapia em …, 2022 - SciELO Brasil
Introduction: Fibromyalgia (FM) is a syndrome of unknown origin characterized by several
symptoms, and although its pathogenesis has not been completely elucidated, it seems to …

[HTML][HTML] Clinical and genetic determinants of vitamin D receptor expression in cutaneous melanoma patients

J De Smedt, C Aura, S Van Kelst, L Janssen… - Melanoma …, 2024 - journals.lww.com
Decrease of vitamin D receptor (VDR) expression is observed in melanocytic naevi and
melanoma compared to normal skin. Little is known about factors influencing VDR …

[HTML][HTML] Interleukin 1 receptor antagonist gene variable number of tandem repeats polymorphism and cutaneous melanoma

S Cauci, C Buligan, F Rocchi, I Salvador… - Oncology …, 2019 - spandidos-publications.com
Immunity and cytokines serve crucial roles in cutaneous melanoma. The present study
investigated whether a variable number tandem repeat (VNTR) polymorphism of interleukin …

Classification of endplate lesions in the lumbar spine and association with risk factors, biochemistry, and genetics

A Colombini, F Galbusera, MC Cortese… - European Spine …, 2021 - Springer
Purpose To detect the associations between the degree of the endplate (EP) lesions with the
presence of risk factors, biochemical and genetic markers previously observed in low back …