[HTML][HTML] Precision medicine becomes reality—tumor type-agnostic therapy

L Yan, W Zhang - Cancer Communications, 2018 - Springer
Precision medicine just witnessed two breakthroughs in oncology in 2017. Pembrolizumab
(Keytruda), Merck's anti-programmed cell death-1 (PD-1) monoclonal antibody (mAb) …

[HTML][HTML] Current update of laboratory molecular diagnostics advancement in management of colorectal cancer (CRC)

SW Pang, NJ Awi, S Armon, WWD Lim, JSH Low… - Diagnostics, 2019 - mdpi.com
Colorectal cancer (CRC) continues to be one of the most common cancers globally. The
incidence has increased in developing countries in the past few decades, this could be …

[HTML][HTML] Genetic Diversity and Population Structure of Metaphire vulgaris Based on the Mitochondrial COI Gene and Microsatellites

Y Fang, J Chen, H Ruan, N Xu, Z Que, H Liu - Frontiers in Genetics, 2021 - frontiersin.org
The earthworm species Metaphire vulgaris (a member of the Clitellata class) is widely
distributed across China, and has important ecological functions and medicinal value …

[HTML][HTML] Morphometric analysis and fluorescent microsatellite markers to evaluate the genetic diversity of five populations of Penaeus japonicus in China

J Du, C Hou, X Chen, J Xiao, Y Gul, H Wang - Aquaculture and Fisheries, 2022 - Elsevier
To understand the current status of germplasm resources of Penaeus japonicus, in this
study, genetic diversity was analyzed based on morphometric analysis and fluorescent …

基于微卫星标记的黄唇鱼遗传多样性研究

赵彦花, 区又君, 温久福, 李加儿, 周慧 - 南方水产科学, 2019 - schinafish.cn
文章利用微卫星标记对珠江口海域19 个黄唇鱼(Bahaba flavolabiata) DNA
样品进行了遗传多样性研究, 以期为黄唇鱼的种质鉴定和保育等研究奠定基础. 结果显示, 29 …

Identification and interpretation of pathogenic variants following Next Generation Sequencing (NGS) analysis in human Mendelian disorders

M Sina - 2023 - iris.unibs.it
During the PhD program the focus was to support diagnostic lab implementing validation or
discover of unusual variants. This is of utmost importance to understand molecular …

Microsatellite instability in colorectal cancer from causes to detection

M Mosallaei, M Simonian, R Salehi - Journal of Cancer Research …, 2021 - journals.lww.com
Sir, Colorectal cancer (CRC) is known as one of the common malignancies in worldwide.
Several studies indicated that 20% of patients have a potential causal genetic component …

CAT25 defines microsatellite instability in colorectal cancer by high-resolution melting PCR

AG Sánchez, I Juaneda, H Eynard… - British Journal of …, 2020 - Taylor & Francis
Background CAT25 (T25mononucleotide repeat of the Caspase 2 gene), is a promising
DNA marker for detecting microsatellite instability (MSI) in colorectal cancer. CAT25 has the …

Precision medicine for colorectal cancer

C Hizel, Ş Tüzmen, A Amirfallah… - … in Cancers and …, 2018 - api.taylorfrancis.com
With the changing demographics of the world population and increasing life expectancy,
prostate cancer has become the most common nonskin cancer in developed countries. The …

[PDF][PDF] Prognostic Significance of Microsatellite Instability in Turkish Patients with Stage II and III Colorectal Cancer

A Deligonul, N Avci, M Kurt, SO Sag, O Isik… - Eurasian Journal of …, 2021 - ejmi.org
Objectives: Microsatellite instability (MSI)–a form of pervasive erratic expansion of
microsatellites–can be identified in 15− 20% of all patients with sporadic colorectal cancer …