Targeting STAT3 in cancer immunotherapy
S Zou, Q Tong, B Liu, W Huang, Y Tian, X Fu - Molecular cancer, 2020 - Springer
As a point of convergence for numerous oncogenic signaling pathways, signal transducer
and activator of transcription 3 (STAT3) is central in regulating the anti-tumor immune …
and activator of transcription 3 (STAT3) is central in regulating the anti-tumor immune …
MicroRNA as a potential therapeutic molecule in cancer
Small noncoding RNAs, as post-translational regulators of many target genes, are not only
markers of neoplastic disease initiation and progression, but also markers of response to …
markers of neoplastic disease initiation and progression, but also markers of response to …
Roles of NF-κB signaling in the regulation of miRNAs impacting on inflammation in cancer
GS Markopoulos, E Roupakia, M Tokamani, G Alabasi… - Biomedicines, 2018 - mdpi.com
The NF-κB family of transcription factors regulate the expression of genes encoding proteins
and microRNAs (miRNA, miR) precursors that may either positively or negatively regulate a …
and microRNAs (miRNA, miR) precursors that may either positively or negatively regulate a …
Role of eicosanoids in liver repair, regeneration and cancer
M de Luján Alvarez, F Lorenzetti - Biochemical pharmacology, 2021 - Elsevier
Eicosanoids are lipid signaling molecules derived from the oxidation of ω-6 fatty acids,
usually arachidonic acid. There are three major pathways, including the cyclooxygenase …
usually arachidonic acid. There are three major pathways, including the cyclooxygenase …
MicroRNA signature in liver cancer
S Ghafouri-Fard, KH Tamizkar, BM Hussen… - Pathology-Research and …, 2021 - Elsevier
Liver cancer is the 7 th utmost frequent neoplasm and the 4 th principal source of cancer
deaths. This malignancy is linked with several environmental and lifestyle-related factors …
deaths. This malignancy is linked with several environmental and lifestyle-related factors …
Long non-coding RNA DLX6-AS1 aggravates hepatocellular carcinoma carcinogenesis by modulating miR-203a/MMP-2 pathway
L Zhang, X He, T Jin, L Gang, Z Jin - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Long non-coding RNAs (lncRNAs) have been wildly verified to modulate multiple
tumorigenesis, especially hepatocellular carcinoma (HCC). In present study, our team aims …
tumorigenesis, especially hepatocellular carcinoma (HCC). In present study, our team aims …
SF3B4 is regulated by microRNA-133b and promotes cell proliferation and metastasis in hepatocellular carcinoma
Z Liu, W Li, Y Pang, Z Zhou, S Liu, K Cheng, Q Qin… - …, 2018 - thelancet.com
Background Splicing factor 3b subunit 4 (SF3B4) is a splicing factor and potential oncogene
in hepatocellular carcinoma (HCC); however, its regulatory mechanism is yet unclear. We …
in hepatocellular carcinoma (HCC); however, its regulatory mechanism is yet unclear. We …
[HTML][HTML] Curcumin inhibits proliferation of epstein–barr virus-associated human nasopharyngeal carcinoma cells by inhibiting EBV nuclear antigen 1 expression
L Liu, J Yang, W Ji, C Wang - BioMed Research International, 2019 - hindawi.com
This investigation aims to study the effect of curcumin on the proliferation, cycle arrest, and
apoptosis of Epstein–Barr virus-(EBV-) positive nasopharyngeal carcinoma (NPC) cells …
apoptosis of Epstein–Barr virus-(EBV-) positive nasopharyngeal carcinoma (NPC) cells …
[HTML][HTML] Circulating microRNAs associated with liver fibrosis in chronic hepatitis C patients
BCA Cabral, L Hoffmann, T Bottaro, PF Costa… - … and Biophysics Reports, 2020 - Elsevier
A major challenge in hepatitis C research is the detection of early potential for progressive
liver disease. MicroRNAs (miRNAs) are small RNAs that regulate gene expression and can …
liver disease. MicroRNAs (miRNAs) are small RNAs that regulate gene expression and can …
Non-alcoholic fatty liver disease: molecular and cellular interplays of the lipid metabolism in a steatotic liver
LF Ramos, CM Silva, CC Pansa… - Expert Review of …, 2021 - Taylor & Francis
Introduction Non-alcoholic fatty liver disease (NAFLD) affects~ 25% of world population and
cases have increased in recent decades. These anomalies have several etiologies; …
cases have increased in recent decades. These anomalies have several etiologies; …