Biomarkers are the key to personalized treatment in patients with breast cancer. While tissue
biomarkers are most useful in determining prognosis and upfront predicting response to …

Although the enumeration of circulating tumor cells (CTC) defined as expressing both
epithelial cell adhesion molecule and cytokeratins (EpCAM+/CK+) can predict prognosis …

ESR1 mutations are important biomarkers in metastatic breast cancer. Specifically, p. E380Q
and p. Y537S mutations arise in response to hormonal therapies given to patients with …

Simple Summary The clinical relevance of tumor genotyping through analysis of ctDNA is
now widely recognized at all steps of the clinical evaluation process in metastatic non-small …

Circulating tumor cells (CTCs) are cells that are shed from tumors into the bloodstream. Cell
enrichment and isolation technology as well as molecular profiling via next-generation …

Introduction: Liquid biopsies have attracted considerable attention as potential diagnostic,
prognostic, predictive, and screening assays in oncology. The term liquid biopsies include …

Retrieval of circulating tumor cells (CTC) has proven valuable for assessing a patient's
cancer burden, evaluating response to therapy, and analyzing which drug might treat a …

Circulating tumor cells (CTCs) have potential utility as a surrogate biomarker of tumor
biology via a liquid biopsy. The aim of this study was to evaluate if the nCounter NanoString …

Purpose: We previously demonstrated that high levels of circulating methylated DNA are
associated with subsequent disease progression in women with metastatic breast cancer …

Breast cancer remains a significant female mortality cause. It constitutes a multifactorial
disease for which research on environmental factors offers little help in predicting onset or …