[HTML][HTML] Targeting the signaling in Epstein–Barr virus-associated diseases: Mechanism, regulation, and clinical study

Y Cao, L Xie, F Shi, M Tang, Y Li, J Hu, L Zhao… - Signal transduction and …, 2021 - nature.com
Epstein–Barr virus-associated diseases are important global health concerns. As a group I
carcinogen, EBV accounts for 1.5% of human malignances, including both epithelial-and …

[HTML][HTML] Current status and future perspectives about molecular biomarkers of nasopharyngeal carcinoma

PY Siak, ASB Khoo, CO Leong, BP Hoh, SC Cheah - Cancers, 2021 - mdpi.com
Simple Summary Nasopharyngeal carcinoma is a serious major public health problem in its
endemic countries. Up to 80% of NPC patients with locally advanced disease or distant …

[HTML][HTML] Upregulation of circRNA_0000285 serves as a prognostic biomarker for nasopharyngeal carcinoma and is involved in radiosensitivity

M Shuai, J Hong, D Huang, X Zhang… - Oncology …, 2018 - spandidos-publications.com
Despite significant medical advancement, nasopharyngeal carcinoma (NPC) remains one of
the most difficult types of cancer to detect and treat. Circular RNA (circRNA) signatures may …

CircRNA_000543 knockdown sensitizes nasopharyngeal carcinoma to irradiation by targeting miR-9/platelet-derived growth factor receptor B axis

L Chen, H Zhou, Z Guan - Biochemical and biophysical research …, 2019 - Elsevier
Radiation therapy is the mainstay of salvage therapy for nasopharyngeal carcinoma (NPC).
However, radiation therapy efficacy is limited by radioresistance that can cause local …

[HTML][HTML] Multiple mechanisms involving in radioresistance of nasopharyngeal carcinoma

Y Zhan, S Fan - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Nasopharyngeal carcinoma (NPC) is the malignant tumor with ethnic and geographical
distribution preference. Although intensity-modulated radiotherapy (IMRT)-based …

[HTML][HTML] DNA methylation biomarkers for nasopharyngeal carcinoma

B Han, X Yang, P Zhang, Y Zhang, Y Tu, Z He, Y Li… - PLoS …, 2020 - journals.plos.org
Background Aberrant methylation of DNA plays an important role in the pathogenesis of
nasopharyngeal carcinoma (NPC). In the current study, we aimed to integrate three cohorts …

Long noncoding RNA PTPRG‐AS1 acts as a microRNA‐194‐3p sponge to regulate radiosensitivity and metastasis of nasopharyngeal carcinoma cells via PRC1

L Yi, L Ouyang, S Wang, SS Li… - Journal of cellular …, 2019 - Wiley Online Library
Protein regulator of cytokinesis 1 (PRC1) has been reported in correlation with various
malignancies. Functionality of PRC1 in nasopharyngeal carcinoma (NPC) was investigated …

[HTML][HTML] ANXA6 contributes to radioresistance by promoting autophagy via inhibiting the PI3K/AKT/mTOR signaling pathway in nasopharyngeal carcinoma

Q Chen, W Zheng, L Zhu, D Yao, C Wang… - Frontiers in cell and …, 2020 - frontiersin.org
Radiotherapy is a conventional and effective treatment method for nasopharyngeal
carcinoma (NPC), although it can fail, mainly because radioresistance results in residual or …

[HTML][HTML] Precision medicine in nasopharyngeal carcinoma: comprehensive review of past, present, and future prospect

PY Siak, WS Heng, SSH Teoh, YY Lwin… - Journal of Translational …, 2023 - Springer
Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with high propensity for
lymphatic spread and distant metastasis. It is prominent as an endemic malignancy in …

[HTML][HTML] Radiation-promoted CDC6 protein stability contributes to radioresistance by regulating senescence and epithelial to mesenchymal transition

X Yu, Y Liu, L Yin, Y Peng, Y Peng, Y Gao, B Yuan… - Oncogene, 2019 - nature.com
Ionizing radiation (IR) is a conventional cancer therapeutic, to which cancer cells develop
radioresistance with exposure. The residual cancer cells after radiation treatment also have …