[HTML][HTML] microRNA therapeutics in cancer—an emerging concept
MY Shah, A Ferrajoli, AK Sood, G Lopez-Berestein… - …, 2016 - thelancet.com
MicroRNAs (miRNAs) are an evolutionarily conserved class of small, regulatory non-coding
RNAs that negatively regulate protein coding gene and other non-coding transcripts …
RNAs that negatively regulate protein coding gene and other non-coding transcripts …
[HTML][HTML] Control of immunoregulatory molecules by miRNAs in T cell activation
A Rodríguez-Galán, L Fernández-Messina… - Frontiers in …, 2018 - frontiersin.org
MiRNA targeting of key immunoregulatory molecules fine-tunes the immune response. This
mechanism boosts or dampens immune functions to preserve homeostasis while supporting …
mechanism boosts or dampens immune functions to preserve homeostasis while supporting …
MicroRNAs: Key modulators of inflammation-associated diseases
Inflammation is a multifaceted biological and pathophysiological response to injuries,
infections, toxins, and inflammatory mechanisms that plays a central role in the progression …
infections, toxins, and inflammatory mechanisms that plays a central role in the progression …
[HTML][HTML] Differential expression of miRNA regulates T cell differentiation and plasticity during visceral leishmaniasis infection
Visceral leishmaniasis (VL) is a tropical neglected disease caused by Leishmania donovani,
results in significant mortality in the Indian subcontinent. The plasticity of T cell proliferation …
results in significant mortality in the Indian subcontinent. The plasticity of T cell proliferation …
MicroRNAs as regulators and effectors of hematopoietic transcription factors
MJ Kim, CI Civin, TJ Kingsbury - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Hematopoiesis is a highly‐regulated development process orchestrated by lineage‐specific
transcription factors that direct the generation of all mature blood cells types, including red …
transcription factors that direct the generation of all mature blood cells types, including red …
The role of microRNAs in the control of innate immune response in cancer
S Jasinski-Bergner, O Mandelboim… - Journal of the National …, 2014 - academic.oup.com
Ligands for receptors of natural killer (NK) cells and CD8+ cytotoxic T lymphocytes (CTL),
such as the inhibitory nonclassical HLA-G, the activating stress-induced major …
such as the inhibitory nonclassical HLA-G, the activating stress-induced major …
Epigenetics in T-cell driven inflammation and cancer
L Falkowski, J Buddenkotte, A Datsi - Seminars in Cell & Developmental …, 2024 - Elsevier
For decades, scientists have been investigating how processes such as gene expression,
stem cell plasticity, and cell differentiation can be modulated. The discovery of epigenetics …
stem cell plasticity, and cell differentiation can be modulated. The discovery of epigenetics …
Cyanidin-3-O-glucoside attenuates lipopolysaccharide-induced inflammation in human corneal epithelial cells by inducing Let-7b-5p-mediated HMGA2/PI3K/Akt …
X Li, M Sun, Y Long - Inflammation, 2020 - Springer
The bacterial keratitis causes viability loss and apoptosis in the corneal epithelial cells
(CECs). The cyanidin-3-O-glucoside (C3G) benefits visual system and also possess anti …
(CECs). The cyanidin-3-O-glucoside (C3G) benefits visual system and also possess anti …
Distinct microRNA profiles for complete hydatidiform moles at risk of malignant progression
LH Lin, I Maestá, JDS Laurent, KT Hasselblatt… - American Journal of …, 2021 - Elsevier
Background MicroRNAs are small noncoding RNAs with important regulatory functions.
Although well-studied in cancer, little is known about the role of microRNAs in premalignant …
Although well-studied in cancer, little is known about the role of microRNAs in premalignant …
[HTML][HTML] A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival
Breast cancer brain metastasis (BCBM) is an area of unmet clinical need. MicroRNAs
(miRNAs) have been linked to the metastatic process in breast cancer (BC). In this study, we …
(miRNAs) have been linked to the metastatic process in breast cancer (BC). In this study, we …