Salivary gland hypofunction and xerostomia in head and neck radiation patients
SB Jensen, A Vissink, KH Limesand… - JNCI …, 2019 - academic.oup.com
Background The most manifest long-term consequences of radiation therapy in the head
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …
Current ideas to reduce or salvage radiation damage to salivary glands
A Vissink, P Van Luijk, JA Langendijk… - Oral diseases, 2015 - Wiley Online Library
Radiation‐induced hyposalivation is still a major problem after radiotherapy for head and
neck cancer. Current and promising new thoughts to reduce or salvage radiation damage to …
neck cancer. Current and promising new thoughts to reduce or salvage radiation damage to …
[HTML][HTML] The significance of the dysregulation of canonical Wnt signaling in head and neck squamous cell carcinomas
J Paluszczak - Cells, 2020 - mdpi.com
The knowledge about the molecular alterations which are found in head and neck
squamous cell carcinomas (HNSCC) has much increased in recent years. However, we are …
squamous cell carcinomas (HNSCC) has much increased in recent years. However, we are …
[PDF][PDF] PERIOD 2 regulates low-dose radioprotection via PER2/pGSK3β/β-catenin/Per2 loop
AT Alexandrou, Y Duan, S Xu, C Tepper, M Fan, J Tang… - Iscience, 2022 - cell.com
During evolution, humans are acclimatized to the stresses of natural radiation and circadian
rhythmicity. Radiosensitivity of mammalian cells varies in the circadian period and adaptive …
rhythmicity. Radiosensitivity of mammalian cells varies in the circadian period and adaptive …
[HTML][HTML] Mechanism, prevention, and treatment of radiation-induced salivary gland injury related to oxidative stress
Z Liu, L Dong, Z Zheng, S Liu, S Gong, L Meng, Y Xin… - Antioxidants, 2021 - mdpi.com
Radiation therapy is a common treatment for head and neck cancers. However, because of
the presence of nerve structures (brain stem, spinal cord, and brachial plexus), salivary …
the presence of nerve structures (brain stem, spinal cord, and brachial plexus), salivary …
[HTML][HTML] Chronic exposure of humans to high level natural background radiation leads to robust expression of protective stress response proteins
Understanding exposures to low doses of ionizing radiation are relevant since most
environmental, diagnostic radiology and occupational exposures lie in this region. However …
environmental, diagnostic radiology and occupational exposures lie in this region. However …
Identification of novel NRAGE involved in the radioresistance of esophageal cancer cells
H Zhou, G Zhang, X Xue, Y Yang, Y Yang, X Chang… - Tumor Biology, 2016 - Springer
Radiotherapy (RT) is one main method for the treatment of esophageal squamous cell
carcinoma (ESCC), and the radioresistance is the predominant cause of patients with local …
carcinoma (ESCC), and the radioresistance is the predominant cause of patients with local …
[HTML][HTML] Fractionated head and neck irradiation impacts taste progenitors, differentiated taste cells, and Wnt/β-catenin signaling in adult mice
Head and neck cancer patients receiving conventional repeated, low dose radiotherapy
(fractionated IR) suffer from taste dysfunction that can persist for months and often years after …
(fractionated IR) suffer from taste dysfunction that can persist for months and often years after …
Licl promotes recovery of radiation-induced oral mucositis and dysgeusia
J Zhu, H Zhang, J Li, X Zheng, X Jia… - Journal of Dental …, 2021 - journals.sagepub.com
Oral mucositis and taste dysfunction are frequently complained by patients with head and
neck cancer receiving radiotherapy, challenging the clinical outcome of cancer treatment …
neck cancer receiving radiotherapy, challenging the clinical outcome of cancer treatment …
Cigarette smoking promotes cancer-related transformation of oral epithelial cells through activation of Wnt and MAPK pathway
Aim: Study aims to investigate the effect of cigarette smoking on cancer-related
transformation in oral epithelial cells of smokers through evaluating the alteration in Wnt/β …
transformation in oral epithelial cells of smokers through evaluating the alteration in Wnt/β …