Melatonin has significant inhibitory effects in numerous cancers, especially breast cancer. In
estrogen receptor (ER)-positive human breast cancer, the oncostatic actions of melatonin …

Breast cancer, a hormone‐dependent tumour, generally includes four molecular subtypes (luminal
A, luminal B, HER2 enriched and triple‐negative) based on oestrogen receptor, …

Immune checkpoint inhibitors (ICIs) induce T-cell activation against cancer cells, and due to
their anti-tumor function in multiple cancers, ICIs have been considered an important option …

Objective Prognostic nutritional index (PNI), calculated as serum albumin (ALB) (g/L) + 5 ×
total lymphocyte count (10 9 /L), is initially used to evaluate nutritional status in patients …

The systemic immune‐inflammation index (SII = N × P/L) based on neutrophil (N), platelet (P)
and lymphocyte (L) counts is used to predict the survival of patients with malignant tumours …

A plethora of previous studies have been focused on the role of indoleamine 2,3-dioxygenase
1 (IDO1) in cancer immunity; however, the alternative way of targeting tryptophan 2,3-…

Previously, several protein-coding tumor suppressors localized at 1p36 have been reported.
In the present work, we focus on functional long non-coding RNAs (lncRNAs) embedded in …

Background and Objective Systemic inflammation response index (SIRI=N×M/L), based on
neutrophil (N), monocyte (M), and lymphocyte (L) counts, is used to predict the survival of …

Background Large cohort studies that estimate the variation in suicide risk among cancer
patients, depending on disease type and patient characteristics, are lacking. We aimed to …

Gut microbiota has emerged as a crucial target of gut-brain axis to influence depression. Zhi-Zi-Chi
decoctions (ZZCD), as a classic oral formula in clinic, is widely applied in depression …