First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows
The second near-infrared wavelength window (NIR-II, 1,000–1,700 nm) enables fluorescence
imaging of tissue with enhanced contrast at depths of millimetres and at micrometre-scale …
imaging of tissue with enhanced contrast at depths of millimetres and at micrometre-scale …
A small-molecule dye for NIR-II imaging
Fluorescent imaging of biological systems in the second near-infrared window (NIR-II) can
probe tissue at centimetre depths and achieve micrometre-scale resolution at depths of …
probe tissue at centimetre depths and achieve micrometre-scale resolution at depths of …
[PDF][PDF] In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles
High temporal and spatial regulation of cellular activities, biological pathways, and gene
expression is critical in complex biological processes.[1] One remarkable technique that …
expression is critical in complex biological processes.[1] One remarkable technique that …
Crucial breakthrough of second near-infrared biological window fluorophores: design and synthesis toward multimodal imaging and theranostics
The development of fluorophores and molecular probes for the second near-infrared biological
window (NIR-II, 1000–1700 nm) represents an important, newly emerging and dynamic …
window (NIR-II, 1000–1700 nm) represents an important, newly emerging and dynamic …
Near-Infrared Fluorescent RGD Peptides for Optical Imaging of Integrin αvβ3 Expression in Living Mice
Z Cheng, Y Wu, Z Xiong, SS Gambhir… - Bioconjugate …, 2005 - ACS Publications
Near-infrared fluorescence optical imaging is a powerful technique for studying diseases at
the molecular level in preclinical models. We recently reported that monomeric RGD peptide …
the molecular level in preclinical models. We recently reported that monomeric RGD peptide …
Diverse applications of nanomedicine
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …
health-related issues continues to receive increasing interest. Research in nanomedicine …
[HTML][HTML] A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)
YH Jin, L Cai, ZS Cheng, H Cheng, T Deng… - Military medical …, 2020 - Springer
In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province;
and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (…
and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (…
[HTML][HTML] A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging
Fluorescence imaging in the second near-infrared window (NIR-II) allows visualization of
deep anatomical features with an unprecedented degree of clarity. NIR-II fluorophores draw …
deep anatomical features with an unprecedented degree of clarity. NIR-II fluorophores draw …
Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects
RH Kimura, Z Cheng, SS Gambhir, JR Cochran - Cancer research, 2009 - AACR
There is a critical need for molecular imaging agents to detect cell surface integrin receptors
that are present in human cancers. Previously, we used directed evolution to engineer …
that are present in human cancers. Previously, we used directed evolution to engineer …
microPET imaging of glioma integrin αvβ3 expression using 64Cu-labeled tetrameric RGD peptide
Integrin α v β 3 plays a critical role in tumor-induced angiogenesis and metastasis and has
become a promising diagnostic indicator and therapeutic target for various solid tumors. …
become a promising diagnostic indicator and therapeutic target for various solid tumors. …