Methods A public database was used to explore the expression and distribution of ACE2 in
normal pancreases. We also retrospectively analyzed patients diagnosed with COVID-19 …

Genetic screening identifies the atypical tetraspanin TM4SF1 as a strong mediator of
metastatic reactivation of breast cancer. Intriguingly, TM4SF1 couples the collagen receptor …

Epigenetic modification plays a crucial regulatory role in the biological processes of eukaryotic
cells. The recent characterization of DNA and RNA methylation is still ongoing. Tumor …

Background Circular RNAs (circRNAs) function as crucial regulators in multiple cancers,
including hepatocellular carcinoma (HCC). However, the roles of circRNAs in HCC remains …

Background Immune cell infiltration in the tumor microenvironment (TME) affects tumor
initiation, patients’ prognosis and immunotherapy strategies. However, their roles and …

A comprehensive overview is presented to summarize the research works since 1982 on
oxidative coupling of methane (OCM), a complex reaction network combining heterogeneous …

Background and Aims Bone is the second most frequent site of metastasis for HCC, which
leads to an extremely poor prognosis. HCC bone metastasis is typically osteolytic, involving …

Interfaces between active metal and metal oxide in a heterogenous catalyst often play an
important role in catalysis. In this work, we intentionally synthesized a series of inverse CeO 2 -…

Therapeutic blockade of the immune checkpoint proteins programmed cell death protein 1 (PD-1)
and cytotoxic T lymphocyte antigen 4 (CTLA4) has transformed cancer treatment. …

More than 90% of anthropogenic carbon emissions are from uses of organic carbon resources
and carbonate minerals that cannot be abandoned any time soon. In this context, we …