Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

…, W Wen, K Matsuo, K Matsuda, C Tanikawa, Z Ren… - Nature …, 2023 - nature.com
Colorectal cancer (CRC) is a leading cause of mortality worldwide. We conducted a genome-wide
association study meta-analysis of 100,204 CRC cases and 154,587 controls of …

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

…, W Wen, G Yang, Y Zhang, C Li, B Li, Y Guo, Z Ren… - Nature …, 2014 - nature.com
Known genetic loci explain only a small proportion of the familial relative risk of colorectal
cancer (CRC). We conducted a genome-wide association study of CRC in East Asians with …

Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer

…, K Matsuo, A Shin, YB Xiang, SH Jee, DH Kim, Z Ren… - Nature …, 2013 - nature.com
To identify new genetic factors for colorectal cancer (CRC), we conducted a genome-wide
association study in east Asians. By analyzing genome-wide data in 2,098 cases and 5,749 …

The impacts of coping style and perceived social support on the mental health of undergraduate students during the early phases of the COVID-19 pandemic in China …

…, H Wang, W Wang, X Gu, L Ma, J Li, S Zhang, Z Ren… - Bmc Psychiatry, 2021 - Springer
Background An increasing number of undergraduate students in China have been reported
to have psychological problems. In response to the COVID-19 pandemic, a series of …

Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer

…, H Shen, SK Park, K Chen, CY Shen, Z Ren… - PLoS …, 2012 - journals.plos.org
Genetic factors play an important role in the etiology of both sporadic and familial breast cancer.
We aimed to discover novel genetic susceptibility loci for breast cancer. We conducted a …

Large-scale genome-wide association study of East Asians identifies loci associated with risk for colorectal cancer

…, B Li, N Wang, B Zhang, X Li, MH Shin, HL Li, Z Ren… - Gastroenterology, 2019 - Elsevier
Background & Aims Genome-wide association studies (GWASs) have associated approximately
50 loci with risk of colorectal cancer (CRC)—nearly one third of these loci were initially …

Identification of susceptibility loci and genes for colorectal cancer risk

…, YT Gao, JH Oh, S Kim, KJ Jung, YO Ahn, Z Ren… - Gastroenterology, 2016 - Elsevier
Background & Aims Known genetic factors explain only a small fraction of genetic variation
in colorectal cancer (CRC). We conducted a genome-wide association study to identify risk …

Genome-wide association study identifies breast cancer risk variant at 10q21. 2: results from the Asia Breast Cancer Consortium

…, K Matsuo, CA Haiman, US Khoo, Z Ren… - Human molecular …, 2011 - academic.oup.com
Although approximately 20 common genetic susceptibility loci have been identified for
breast cancer risk through genome-wide association studies (GWASs), genetic risk variants …

Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls

…, H Shen, K Chen, PE Wu, Z Ren… - Human molecular …, 2013 - academic.oup.com
In a consortium including 23 637 breast cancer patients and 25 579 controls of East Asian
ancestry, we investigated 70 single-nucleotide polymorphisms (SNPs) in 67 independent …

Plasma miR-221 as a predictive biomarker for chemoresistance in breast cancer patients who previously received neoadjuvant chemotherapy

R Zhao, J Wu, W Jia, C Gong, F Yu, Z Ren… - Oncology Research …, 2011 - karger.com
Background: Neoadjuvant chemotherapy (NAC) is increasingly being used in breast cancer
treatment. Research has revealed an elevated expression of miR-221 in adriamycinresistant …