A novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancer

H Zong, X Li, L Han, L Wang, J Liu, Y Yue… - Acta Pharmacologica …, 2024 - nature.com
Antibody drug conjugate (ADC) therapy has become one of the most promising approaches
in cancer immunotherapy. Bispecific targeting could enhance the efficacy and safety of ADC …

Long-term passaging of pseudo-typed SARS-CoV-2 reveals the breadth of monoclonal and bispecific antibody cocktails

H Ma, H Zong, J Liu, Y Yue, Y Ke, Y Liao… - Acta Pharmacologica …, 2023 - nature.com
The continuous emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants poses challenges to the effectiveness of neutralizing antibodies. Rational design …

[HTML][HTML] Paclitaxel-etoposide-carboplatin/cisplatin versus etoposide-carboplatin/cisplatin as first-line treatment for combined small-cell lung cancer: a retrospective …

YY Li, C Zhou, DX Yang, J Wang, ZJ Liu… - Cancer Biology & …, 2015 - ncbi.nlm.nih.gov
Objective To compare the efficacy and adverse effects of paclitaxel-etoposide-carboplatin/cisplatin
(TEP/TCE) regimen with those of etoposide-carboplatin/cisplatin (EP/CE) regimen as …

Diosgenin inhibits the proliferation of MCF-7 breast cancer cells through the demethylation of miR-145 gene

F Shi, L Lu, Y Li, L Hou, X Chen, H Rui, C Wang, Y Yue - Cancer Research, 2018 - AACR
Background: Altered DNA methylation in microRNA (miRNA) host genes has been frequently
associated with abnormal miRNA expression during the pathogenesis of cancer. miR-145 …

Petrogenesis of Middle–Late Triassic volcanic rocks from the Gangdese belt, southern Lhasa terrane: Implications for early subduction of Neo-Tethyan oceanic …

C Wang, L Ding, LY Zhang, P Kapp, A Pullen, YH Yue - Lithos, 2016 - Elsevier
The Gangdese belt is dominantly composed of igneous rocks that formed during the
northward subduction of Neo-Tethyan oceanic lithosphere beneath the Lhasa terrane and has …

The latest Jurassic protoliths of the Sangsang mafic schists in southern Tibet: Implications for the spatial extent of Greater India

HQ Wang, L Ding, FL Cai, YL Sun, S Li, YH Yue… - Gondwana …, 2020 - Elsevier
Field observations, petrology, zircon geochronology, whole-rock geochemistry, and Sr-Nd
isotopes were used to reveal the lithology, age, and tectonic setting of the protoliths of the …

Numerical Analysis and Measuring for The Potential Distribution of 800kV MOA

YL Yue, SC Jiang, YB Zhang - 2008 China International …, 2008 - ieeexplore.ieee.org
Numerical analysis and measuring for the potential distribution of 800 kV MOA are introduced
in the paper. Firstly, the potential distribution of 800 kV MOA with no parallel connection of …

Investigation on toxicity mechanism of halogenated aromatic disinfection by-products to zebrafish based on molecular docking and QSAR model

JJ Li, YX Yue, SJ Shi, JZ Xue - Chemosphere, 2023 - Elsevier
Halogenated aromatic disinfection by-products (DBPs) are a new type of DBPs that have
been detected in various water bodies. Previous studies have shown that most of them can …

Identification and analysis of the type of leaf variegation of Primulina pungentisepala.

Y Li, D He, J Chen, B Li, M Bai, L Luo, Q Zhang - 2022 - cabidigitallibrary.org
Several features of Primulina pungentisepala leaf to determine the type of leaf variegation
were analyzed. These features include:the morphological characteristics of leaf epidermis, the …

Evolution of the Sumdo Paleo-Tethyan Ocean: Constraints from Permian Luobadui Formation in Lhasa terrane, South Tibet

C Wang, L Ding, FL Cai, HQ Wang, LY Zhang… - Palaeogeography …, 2022 - Elsevier
Reconstructing the evolution of the Sumdo Paleo-Tethyan Ocean (SPTO) is important for
understanding the transition from the Paleo-Tethyan system to the Neo-Tethyan system. The …