Currently, environmental pollution by heavy metals is a global problem. Therefore, it is
crucial to develop effective detection techniques to determine the levels of heavy metal …

De novo and acquired resistance, which are largely attributed to genetic alterations, are
barriers to effective anti-epidermal-growth-factor-receptor (EGFR) therapy. To generate …

Elucidating the mechanisms by which short chain fatty acids (SCFA) reduce body weight may
assist in the development of an effective weight control strategy. Dietary supplementation …

Coarse TiC particles (more than 50 μm) reinforced H13 steel composites produced by laser
cladding with various ceramic volume fraction were investigated. The effects of the ceramic …

Introduction: Metastasis and drug resistance contribute substantially to the poor prognosis of
colorectal cancer (CRC) patients. However, the epigenetic regulatory mechanisms by which …

Following dramatic success in many types of advanced solid tumors, interest in
immunotherapy for the treatment of colorectal cancer (CRC) is increasingly growing. Given the …

Background Epithelial-to-mesenchymal transition (EMT) is a process linked to metastasis
and drug resistance with non-coding RNAs (ncRNAs) playing pivotal roles. We previously …

Accumulating evidence suggests small non-coding RNAs (microRNAs) play important roles
in human cancer progression. In the present study, we found miR-150 was overexpressed in …

Monascus azaphilone pigments (MonAzPs) are very widely used as food colorants, but their
biosynthetic pathway has remained poorly characterized for more than half a century. In this …

Epithelial-to-mesenchymal transition (EMT) induced by chronic hypoxia is one of the critical
causes of renal fibrosis. Twist, a basic helix-loop-helix transcription factor, is believed to be …