Scientific considerations of pharmaceutical solid polymorphism in abbreviated new drug applications

…, F Fang, RM Patel, FO Holcombe, Y Chiu… - Pharmaceutical …, 2003 - Springer
Purpose. This commentary is intended to provide a scientific perspective on pharmaceutical
solid polymorphism in Abbreviated New Drug Applications (ANDAs). Methods. This report …

Up-regulation thioredoxin inhibits advanced glycation end products-induced neurodegeneration

X Ren, N Wang, H Qi, Y Qiu, C Zhang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Diabetic retinopathy (DR) is one of the most serious complications of diabetes
and is the leading cause of adult blindness in developed countries. Advanced glycation …

FDA perspective on peptide formulation and stability issues

CH Niu, YY Chiu - Journal of pharmaceutical sciences, 1998 - Wiley Online Library
Traditionally, peptide drugs are prepared as sterile solutions and administered to patients
by daily injection. However, this form of drug delivery causes pain and inconvenience to …

Combination of microwave ablation and percutaneous osteoplasty for treatment of painful extraspinal bone metastasis

YY Qiu, KX Zhang, X Ye, XS Zhang, C Xing… - Journal of Vascular and …, 2019 - Elsevier
… Author links open overlay panel Yuan-Yuan Qiu MD a , Kai-Xian Zhang MD, PhD a , Xin Ye
MD, PhD c , Xu-Sheng Zhang MD a , Chao Xing MD a , Qing-Song Wu MD b , Miao-Miao Hu …

[PDF][PDF] Topological transformation of dual polyhedral links

D Lu, G Hu, YY Qiu, WY Qiu - MATCH Commun. Math. Comput …, 2010 - researchgate.net
In this paper, the novel topology of Platonic polyhedral links is discussed on the basis of the
graph theory and topological principles. This interesting problem of the dual polyhedral links …

Difference-frequency ultrasound generation from microbubbles under dual-frequency excitation

M Qing-Yu, Q Yuan-Yuan, H Bei, Z Dong… - Chinese Physics …, 2010 - iopscience.iop.org
The difference-frequency (DF) ultrasound generated by using parametric effect promises to
improve detection depth owing to its low attenuation, which is beneficial for deep tissue …

Studies on photosynthesis, respiration and morphology of Nostoc flagelliforme

S Ding-ji, Z Guo-fei, F Zhao-xi, Q Yuan-yuan… - Journal of Integrative …, 1992 - jipb.net
Abstract: Nostoc flagelliforme Born. et Flah. is one of the terrestrial cyanobacteria naturally
distributed in arid and semi-arid areas in the Northern and the North-western parts of China. …

Modeling of shock wave generated from a strong focused ultrasound transducer

T Chen, YY Qiu, TB Fan, D Zhang - Chinese Physics Letters, 2013 - iopscience.iop.org
A combined time and frequency domain method is developed for the calculation of a shock
wave induced by a strong focused ultrasound transducer in the oblate spheroidal coordinate …

Regulatory concerns for the chemistry, manufacturing, and controls of oligonucleotide therapeutics for use in clinical studies

RAOVB KAMBHAMPATI, YY CHIU… - Antisense Research …, 1993 - liebertpub.com
It is important to remember that while a new class of therapeutic agents like oligonucleotides
may introduce novel concerns, the basic regulatory issues regarding the chemistry, …

Crystal and molecular structure of complex between cyclo (L-prolylglycyl) 4 and rubidium thiocyanate

YY Chiu, LD Brown, WN Lipscomb - Journal of the American …, 1977 - ACS Publications
The cyclic octapeptide c> Wo (L-prolylglycyl) 4 yields, with rubidium thiocyanate in acetone-water,
crystals having the formulac (L-Pro-Gly) 4-RbSCN-3H20. Three-dimensional x-ray …