The purpose of this study was to determine the safety, distribution, internal dosimetry, and
initial human epidermal growth factor receptor 2 (HER2)–positive tumor images of 64 Cu-…

Among the various types of oligosaccharide structures, asparagine-linked oligosaccharides
(N-glycans) are the most prominent in terms of diversity and complexity. In particular, N-…

Background The purpose of this study was to determine whether brain metastases from
HER2-positive breast cancer could be detected noninvasively using positron emission …

By using a prototype Compton camera consisting of silicon (Si) and cadmium telluride (CdTe)
semiconductor detectors, originally developed for the ASTRO-H satellite mission, an …

Our recent work suggested that intranasal coadministration with the cell-penetrating peptide
(CPP) penetratin increased the brain distribution of the peptide drug insulin. The present …

Normal brain aging is commonly associated with neural activity alteration, β-amyloid (Aβ)
deposition, and tau aggregation, driving a progressive cognitive decline in normal elderly …

We have demonstrated the feasibility of semiconductor Compton cameras for multiple
molecular imaging in nuclear medicine. The Compton camera used in this work comprises two …

The insufficient energy and spatial resolutions of radionuclide imaging with conventional
scintillation detectors restrict the visualization of multiple radionuclides and of microstructures in …

α-Emission radiotherapeutics has potential to be one of most effective cancer therapeutics.
Herein, we report a facile synthesis of an 211At-labeled immunoconjugate for use as an α-…

Molecular imaging technique by use of positron emission tomography (PET) is a noninvasive
tool that allows one to quantitatively analyze the function of endogenous molecules and …