Nasopharyngeal carcinoma (NPC) is a rare malignancy with an extraordinarily skewed
geographic distribution worldwide. Although decreasing trends in incidence and mortality of NPC …

Background Genetic variation has an important role in the development of non-small-cell
lung cancer (NSCLC). However, genetic factors for lung cancer have not been fully identified, …

The oral microbiota has been observed to be influenced by cigarette smoking and linked to
several human diseases. However, research on the effect of cigarette smoking on the oral …

BRCA2 gene plays an important role in homologous recombination. Polymorphic variants in
this gene has been suggested to confer cancer susceptibility. Numerous studies have …

Polygenic risk scores (PRS) have the potential to identify individuals at risk of diseases,
optimizing treatment, and predicting survival outcomes. Here, we construct and validate a …

Background The human leukocyte antigen (HLA) is a highly polymorphic region, and HLA
diversity may play a role in presenting tumour-associated peptides and inducing immune …

The dysbiosis of oral microbiota is linked to numerous diseases and is associated with personal
lifestyles, such as alcohol drinking. However, there is inadequate data to study the effect …

Background The difference in epidemiological characteristics of breast cancer (BC) across
countries is valuable for BC management and prevention. The study evaluated the up-to-date …

Background Radiation-induced oral mucositis (OM) is one of the most common acute
complications for head and neck cancer. Severe OM is associated with radiation treatment breaks, …

Various biomarkers targeting cell-free DNA (cfDNA) and circulating proteins have been tested
for pan-cancer detection. Oncofetal chondroitin sulfate (ofCS), which distinctively modifies …