Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells
Both human embryonic stem cells and induced pluripotent stem cells can self-renew indefinitely
in culture; however, present methods to clonally grow them are inefficient and poorly …
in culture; however, present methods to clonally grow them are inefficient and poorly …
Biomaterials for bioprinting microvasculature
Microvasculature functions at the tissue and cell level, regulating local mass exchange of
oxygen and nutrient-rich blood. While there has been considerable success in the …
oxygen and nutrient-rich blood. While there has been considerable success in the …
Combinatorial discovery of polymers resistant to bacterial attachment
Bacterial attachment and subsequent biofilm formation pose key challenges to the optimal
performance of medical devices. In this study, we determined the attachment of selected …
performance of medical devices. In this study, we determined the attachment of selected …
3D bioprinting for vascularized tissue fabrication
3D bioprinting holds remarkable promise for rapid fabrication of 3D tissue engineering
constructs. Given its scalability, reproducibility, and precise multi-dimensional control that …
constructs. Given its scalability, reproducibility, and precise multi-dimensional control that …
Engineering alginate as bioink for bioprinting
Recent advances in three-dimensional (3-D) printing offer an excellent opportunity to address
critical challenges faced by current tissue engineering approaches. Alginate hydrogels …
critical challenges faced by current tissue engineering approaches. Alginate hydrogels …
[HTML][HTML] The role of ferroptosis in cancer development and treatment response
B Lu, XB Chen, MD Ying, QJ He, J Cao… - Frontiers in …, 2018 - frontiersin.org
Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell
death, which is a distinct regulated cell death comparing to other cell death. The lethal …
death, which is a distinct regulated cell death comparing to other cell death. The lethal …
[HTML][HTML] A targetable LIFR− NF-κB− LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
The growing knowledge of ferroptosis has suggested the role and therapeutic potential of
ferroptosis in cancer, but has not been translated into effective therapy. Liver cancer, primarily …
ferroptosis in cancer, but has not been translated into effective therapy. Liver cancer, primarily …
Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity
Environmental factors are the largest contributors to cardiovascular disease. Here we show
that cardiac organoids that incorporate an oxygen-diffusion gradient and that are stimulated …
that cardiac organoids that incorporate an oxygen-diffusion gradient and that are stimulated …
Recent developments and future perspectives of reverse electrodialysis technology: A review
Reverse electrodialysis (RED) is an emerging membrane based technology that captures
electricity from controlled mixing of two water streams of different salinities. To date, great …
electricity from controlled mixing of two water streams of different salinities. To date, great …
Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles
Stem cells hold great potential as cell-based therapies to promote vascularization and
tissue regeneration. However, the use of stem cells alone to promote angiogenesis remains …
tissue regeneration. However, the use of stem cells alone to promote angiogenesis remains …