[HTML][HTML] LncRNAs: from basic research to medical application

T Wu, Y Du - International journal of biological sciences, 2017 - ncbi.nlm.nih.gov
This review aimed to summarize the current research contents about long noncoding RNAs (lncRNAs)
and some related lncRNAs as molecular biomarkers or therapy strategies in …

Epigenetic alterations as cancer diagnostic, prognostic, and predictive biomarkers

D Deng, Z Liu, Y Du - Advances in genetics, 2010 - Elsevier
Alterations of DNA methylation and transcription of microRNAs (miRNAs) are very stable
phenomena in tissues and body fluids and suitable for sensitive detection. These advantages …

Upregulation of myosin Va by Snail is involved in cancer cell migration and metastasis

L Lan, H Han, H Zuo, Z Chen, Y Du… - … Journal of Cancer, 2010 - Wiley Online Library
Cell migration, which involves acto‐myosin dynamics, cell adhesion, membrane trafficking
and signal transduction, is a prerequisite for cancer cell metastasis. Here, we report that an …

Serum exosomal MiR-92b-5p as a potential biomarker for acute heart failure caused by dilated cardiomyopathy

T Wu, Y Chen, Y Du, J Tao, Z Zhou… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: MicroRNAs (miRNAs) can be used as biomarkers for cardiovascular
diseases, especially for heart failure. However, there are few reports on serum exosomal miRNA …

[HTML][HTML] PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells

H Han, Y Du, W Zhao, S Li, D Chen, J Zhang… - Nature …, 2015 - nature.com
Tumour-initiating cells (TICs) are advocated to constitute the sustaining force to maintain and
renew fully established malignancy; however, the molecular mechanisms responsible for …

[HTML][HTML] MALAT1miR663a negative feedback loop in colon cancer cell functions through direct miRNA–lncRNA binding

W Tian, Y Du, Y Ma, L Gu, J Zhou, D Deng - Cell death & disease, 2018 - nature.com
The lncRNA MALAT1 has multiple biological functions, including influencing RNA processing,
miRNA sponging, and cancer development. It is acknowledged that miR663a and its …

[HTML][HTML] Circulating exosomal miR-92b-5p is a promising diagnostic biomarker of heart failure with reduced ejection fraction patients hospitalized for acute heart failure

T Wu, Y Chen, Y Du, J Tao, W Li, Z Zhou… - Journal of Thoracic …, 2018 - ncbi.nlm.nih.gov
Background Circulating microRNA (miRNA) biomarkers have been extensively reported in
cardiovascular diseases (CVDs). However, serum exosomal miRNA (exo-miRNA) as …

miR-137 plays tumor suppressor roles in gastric cancer cell lines by targeting KLF12 and MYO1C

Y Du, Y Chen, F Wang, L Gu - Tumor Biology, 2016 - Springer
Aberrant expression of miR-137 has been reported in many kinds of cancers, but its mechanisms
seem to be diversely. In the present study, we compared the expression level of miR-…

[HTML][HTML] LncRNA miR663AHG represses the development of colon cancer in a miR663a-dependent manner

H Yuan, Q Ren, Y Du, Y Ma, L Gu, J Zhou, W Tian… - Cell Death …, 2023 - nature.com
The MIR663AHG gene encodes both miR663AHG and miR663a. While miR663a contributes
to the defense of host cells against inflammation and inhibits colon cancer development, …

[PDF][PDF] Peking: Building semantic dependency graphs with a hybrid parser

Y Du, F Zhang, X Zhang, W Sun… - Proceedings of the 9th …, 2015 - aclanthology.org
This paper is a description of our system for SemEval-2015 Task 18: Broad-Coverage Semantic
Dependency Parsing. We implement a hybrid parser which benefits from both transition-…