3D culture technologies of cancer stem cells: promising ex vivo tumor models
…, JC Knowles, HW Kim, GZ Jin, Y Xuan - Journal of tissue …, 2020 - journals.sagepub.com
Cancer stem cells have been shown to be important in tumorigenesis processes, such as
tumor growth, metastasis, and recurrence. As such, many three-dimensional models have …
tumor growth, metastasis, and recurrence. As such, many three-dimensional models have …
GLI1 promotes cancer stemness through intracellular signaling pathway PI3K/Akt/NFκB in colorectal adenocarcinoma
Z Yang, C Zhang, W Qi, Y Cui, Y Xuan - Experimental Cell Research, 2018 - Elsevier
The role of Hedgehog (HH)/ glioma-associated oncogene homolog 1 (GLI1) pathway has
been implicated in a variety of cancer entities, and the targeted pathway inhibition mediated by …
been implicated in a variety of cancer entities, and the targeted pathway inhibition mediated by …
Gli1, a potential regulator of esophageal cancer stem cell, is identified as an independent adverse prognostic factor in esophageal squamous cell carcinoma
Z Yang, Y Cui, W Ni, S Kim, Y Xuan - Journal of cancer research and …, 2017 - Springer
Purpose The hedgehog (Hh) pathway is involved in cancer stem cell (CSC) maintenance in
various tumors. Glioma-associated oncogene homolog 1 (Gli1) is a key mediator of the Hh …
various tumors. Glioma-associated oncogene homolog 1 (Gli1) is a key mediator of the Hh …
Tenascin C is a prognostic determinant and potential cancer-associated fibroblasts marker for breast ductal carcinoma
Z Yang, W Ni, C Cui, L Fang, Y Xuan - Experimental and molecular …, 2017 - Elsevier
Tenascin C (TNC) is a key of extracellular matrix glycoprotein and highly express in numerous
human malignancies. Herein, we attempted to clarify the clinicopathological significance …
human malignancies. Herein, we attempted to clarify the clinicopathological significance …
[HTML][HTML] Tenascin-C predicts poor outcomes for patients with colorectal cancer and drives cancer stemness via Hedgehog signaling pathway
…, C Zhang, Y Feng, M Quan, Y Cui, Y Xuan - Cancer cell international, 2020 - Springer
Background Tenascin-C (TNC) is an extracellular matrix protein that is widely expressed in
the stromal fibroblasts of various cancers. However, the roles of TNC in colorectal cancer (…
the stromal fibroblasts of various cancers. However, the roles of TNC in colorectal cancer (…
Tenascin-C as a prognostic determinant of colorectal cancer through induction of epithelial-to-mesenchymal transition and proliferation
Z Yang, C Zhang, W Qi, C Cui, Y Cui, Y Xuan - Experimental and Molecular …, 2018 - Elsevier
Although Tenascin-C (TNC) as an extracellular matrix protein involved in various cancers, the
mechanisms by which TNC leads to decreased survival time remain to be clarified in CRC. …
mechanisms by which TNC leads to decreased survival time remain to be clarified in CRC. …
[HTML][HTML] SETD5 regulates the OGT-catalyzed O-GlcNAcylation of RNA polymerase II, which is involved in the stemness of colorectal cancer cells
HI Cho, S Jo, MS Kim, HB Kim, X Liu, Y Xuan… - Scientific Reports, 2023 - nature.com
The dosage-dependent recruitment of RNA polymerase II (Pol II) at the promoters of genes
related to neurodevelopment and stem cell maintenance is required for transcription by the …
related to neurodevelopment and stem cell maintenance is required for transcription by the …
Identification of LETM1 as a marker of cancer stem-like cells and predictor of poor prognosis in esophageal squamous cell carcinoma
Z Yang, W Ni, C Cui, W Qi, L Piao, Y Xuan - Human pathology, 2018 - Elsevier
Leucine zipper–EF-hand containing transmembrane protein 1 (LETM1) is closely related to
the occurrence and development of malignant tumors. This study discusses the expression …
the occurrence and development of malignant tumors. This study discusses the expression …
Clinicopathological significance of DEK overexpression in serous ovarian tumors
S Han, Y Xuan, S Liu, M Zhang, D Jin… - Pathology …, 2009 - Wiley Online Library
To investigate the significance of DEK protein expression in ovarian lesions, a total of 113
ovarian serous tumors, including 62 serous cystadenocarcinomas and 19 serous borderline …
ovarian serous tumors, including 62 serous cystadenocarcinomas and 19 serous borderline …
Tenascin-C is a potential cancer-associated fibroblasts marker and predicts poor prognosis in prostate cancer
…, ZT Yang, CA Cui, Y Cui, LY Fang, YH Xuan - … and biophysical research …, 2017 - Elsevier
Tenascin-C (TNC), as a member of the extracellular matrix (ECM), plays an important role in
cancer cell proliferation and migration and tumor invasion in various types of cancer. Here, …
cancer cell proliferation and migration and tumor invasion in various types of cancer. Here, …