A ras-related gene with transformation suppressor activity
H Kitayama, Y Sugimoto, T Matsuzaki, Y Ikawa… - Cell, 1989 - cell.com
A 1.8 kb cDNA clone, Krev-1, with revertant-inducing activity on Kirsten sarcoma virus-transformed
NIHI 3T3 cells, has been isolated from a human fibroblast cDNA expression library. In …
NIHI 3T3 cells, has been isolated from a human fibroblast cDNA expression library. In …
Calcium oxide as a solid base catalyst for transesterification of soybean oil and its application to biodiesel production
M Kouzu, T Kasuno, M Tajika, Y Sugimoto… - Fuel, 2008 - Elsevier
In order to study solid base catalyst for biodiesel production with environmental benignity,
transesterification of edible soybean oil with refluxing methanol was carried out in the …
transesterification of edible soybean oil with refluxing methanol was carried out in the …
C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance
…, E Ishikawa, T Tsuruo, Y Miki, Y Sugimoto - Molecular cancer …, 2002 - AACR
Breast cancer resistance protein (BCRP) confers multidrug resistance to cancer cells against
agents such as SN-38 (an active metabolite of irinotecan), mitoxantrone, and topotecan. …
agents such as SN-38 (an active metabolite of irinotecan), mitoxantrone, and topotecan. …
Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol.
Y Sugimoto, M Whitman, LC Cantley… - Proceedings of the …, 1984 - National Acad Sciences
The ability of purified Rous sarcoma virus transforming gene product, pp60v-src, to phosphorylate
phosphatidylinositol and diacylglycerol was investigated. Phosphatidylinositol was …
phosphatidylinositol and diacylglycerol was investigated. Phosphatidylinositol was …
Dominant‐negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S‐S dependent homodimerization
…, E Ishikawa, T Tsuruo, Y Sugimoto - … journal of cancer, 2002 - Wiley Online Library
Breast cancer resistance protein (BCRP) is a half‐molecule ABC transporter highly
expressed in mitoxantrone‐resistant cells. In our study we established PA317 transfectants …
expressed in mitoxantrone‐resistant cells. In our study we established PA317 transfectants …
α-Galactosidase A deficient mice: a model of Fabry disease
…, JM Quirk, CO Cardarelli, Y Sugimoto… - Proceedings of the …, 1997 - National Acad Sciences
Fabry disease is an X-linked inherited metabolic disorder that is caused by a deficiency of α-galactosidase
A (α-Gal A). Progressive deposition of neutral glycosphingolipids that have …
A (α-Gal A). Progressive deposition of neutral glycosphingolipids that have …
[HTML][HTML] ABCG2 transports sulfated conjugates of steroids and xenobiotics
M Suzuki, H Suzuki, Y Sugimoto, Y Sugiyama - Journal of Biological …, 2003 - ASBMB
The mechanism for the cellular extrusion of sulfated conjugates is still unknown. In the present
study, we investigated whether human wild type ABCG2 transports estrone 3-sulfate (E 1 …
study, we investigated whether human wild type ABCG2 transports estrone 3-sulfate (E 1 …
Transport of Methotrexate, Methotrexate Polyglutamates, and 17β-Estradiol 17-(β-d-glucuronide) by ABCG2: Effects of Acquired Mutations at R482 on Methotrexate …
…, MG Belinsky, I Shchaveleva, XQ Ren, Y Sugimoto… - Cancer research, 2003 - AACR
ABCG2 is a plasma membrane efflux pump that is able to confer resistance to several
anticancer agents, including mitoxantrone, camptothecins, anthracyclines, and flavopiridol. The …
anticancer agents, including mitoxantrone, camptothecins, anthracyclines, and flavopiridol. The …
Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance
Y Imai, S Tsukahara, S Asada, Y Sugimoto - Cancer research, 2004 - AACR
Breast cancer resistance protein (BCRP), also called ABCG2, confers resistance to anticancer
agents such as 7-ethyl-10-hydroxycamptothecin (SN-38), mitoxantrone, and topotecan. …
agents such as 7-ethyl-10-hydroxycamptothecin (SN-38), mitoxantrone, and topotecan. …
Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin
…, Y Fujiwara, K Nishio, T Ohmori, Y Sugimoto… - Cancer research, 1991 - AACR
We have established cis-diamminedichloroplatinum(II) (cisplatin) resistant human small cell
lung cancer cell lines, H69/CDDP 0.2 and H69/CDDP, to investigate the mechanism of …
lung cancer cell lines, H69/CDDP 0.2 and H69/CDDP, to investigate the mechanism of …