Overexpression of yes‐associated protein contributes to progression and poor prognosis of non‐small‐cell lung cancer

…, Q Dong, Q Zhang, Z Li, E Wang, X Qiu - Cancer science, 2010 - Wiley Online Library
Yes‐associated protein (YAP), the nuclear effector of the Hippo pathway, is a key regulator
of organ size and a candidate human oncogene. This study aimed to assess the clinical …

[HTML][HTML] Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer …

L Jiang, Q Huang, S Zhang, Q Zhang, J Chang, X Qiu… - BMC cancer, 2010 - Springer
Background Two mature microRNAs (miRNAs), hsa-miR-125a-3p and hsa-miR-125a-5p (collectively
referred to as hsa-miR-125a-3p/5p), are derived from 3' and 5' ends of pre-miR-…

[HTML][HTML] The role of melatonin in the development of postmenopausal osteoporosis

K Yang, X Qiu, L Cao, S Qiu - Frontiers in pharmacology, 2022 - frontiersin.org
Melatonin is an important endogenous hormone that modulates homeostasis in the
microenvironment. Recent studies have indicated that serum melatonin levels are closely associated …

[HTML][HTML] MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met

W Luo, BO Huang, Z Li, H Li, L Sun, Q Zhang, X Qiu… - PloS one, 2013 - journals.plos.org
MicroRNA-449a is expressed at a low level in several tumors and cancer cell lines, and
induces G1 arrest, apoptosis, and senescence. To identify the function of miR-449a in non-small …

M2 macrophage infiltration into tumor islets leads to poor prognosis in non-small-cell lung cancer

L Cao, X Che, X Qiu, Z Li, B Yang, S Wang… - Cancer management …, 2019 - Taylor & Francis
Background: Lung cancer is the leading cause of cancer-related death worldwide. Although
the macrophages can affect the development of tumor, the contribution of macrophages to …

[HTML][HTML] Prognostic significance of twist and N-cadherin expression in NSCLC

L Hui, S Zhang, X Dong, D Tian, Z Cui, X Qiu - PloS one, 2013 - journals.plos.org
Background Metastasis is the most common cause of disease failure and mortality for non-small
cell lung cancer after surgical resection. Twist has been recently identified as a putative …

[HTML][HTML] Overexpression of TRIM24 correlates with tumor progression in non-small cell lung cancer

H Li, L Sun, Z Tang, L Fu, Y Xu, Z Li, W Luo, X Qiu… - PloS one, 2012 - journals.plos.org
The objective of the current study was to investigate the expression pattern and clinicopathological
significance of TRIM24 in patients with non-small cell lung cancer (NSCLC). The …

PRL-3 facilitates angiogenesis and metastasis by increasing ERK phosphorylation and up-regulating the levels and activities of Rho-A/C in lung cancer

J Ming, N Liu, Y Gu, X Qiu, EH Wang - Pathology, 2009 - Taylor & Francis
Aims: The aim of this study was to investigate the mechanism of PRL-3 in inducing angiogenesis
and lymphangiogenesis to promote distant and lymph node metastasis in human lung …

Inhibition of cytoplasmic GSK-3β increases cisplatin resistance through activation of Wnt/β-catenin signaling in A549/DDP cells

…, Z Liu, X Zhang, J He, Y Pan, F Hao, L Xie, Q Li, X Qiu… - Cancer letters, 2013 - Elsevier
Cisplatin-based chemotherapy is recommended as the first-line therapy for advanced non-small
cell lung cancer (NSCLC). However, acquired cisplatin resistance is ubiquitous in …

Hypoxia-induced CCR7 expression via HIF-1α and HIF-2α correlates with migration and invasion in lung cancer cells

Y Li, X Qiu, S Zhang, Q Zhang… - Cancer Biology & Therapy, 2009 - Taylor & Francis
Hypoxia, a common phenomenon in human solid tumors, is associated with invasion and
metastasis in various tumors. Hypoxia inducible factors (HIFs) are key molecules in the …