[HTML][HTML] RSL3 drives ferroptosis through GPX4 inactivation and ROS production in colorectal cancer
…, S Liu, T Duan, L Zhai, M Zhang, X Han… - Frontiers in …, 2018 - frontiersin.org
Ferroptosis is an iron-dependent, oxidative cell death, and is characterized by iron-dependent
accumulation of reactive oxygen species (ROS) within the cell. It has been implicated in …
accumulation of reactive oxygen species (ROS) within the cell. It has been implicated in …
[HTML][HTML] Erianin, a novel dibenzyl compound in Dendrobium extract, inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis
…, B Zhai, W Wang, R Zhang, B Chen, X Han… - Signal transduction and …, 2020 - nature.com
Ferroptosis, a novel form of programmed cell death, is characterized by iron-dependent lipid
peroxidation and has been shown to be involved in multiple diseases, including cancer. …
peroxidation and has been shown to be involved in multiple diseases, including cancer. …
[HTML][HTML] Molecular targets of β-elemene, a herbal extract used in traditional Chinese medicine, and its potential role in cancer therapy: A review
B Zhai, N Zhang, X Han, Q Li, M Zhang, X Chen… - Biomedicine & …, 2019 - Elsevier
β-Elemene is a sesquiterpene compound extracted from the herb Curcuma Rhizoma and is
used in traditional Chinese medicine (TCM) to treat several types of cancer, with no reported …
used in traditional Chinese medicine (TCM) to treat several types of cancer, with no reported …
[HTML][HTML] The mechanism of m6A methyltransferase METTL3-mediated autophagy in reversing gefitinib resistance in NSCLC cells by β-elemene
S Liu, Q Li, G Li, Q Zhang, L Zhuo, X Han… - Cell death & …, 2020 - nature.com
N 6 -methyladenosine (m 6 A) modification can alter gene expression by regulating RNA
splicing, stability, translocation, and translation. Emerging evidence shows that m 6 A …
splicing, stability, translocation, and translation. Emerging evidence shows that m 6 A …
[HTML][HTML] PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death
…, W Wang, R Zhang, B Chen, M Zhang, X Han… - Signal transduction and …, 2019 - nature.com
5-Fluorouracil (5-FU) is known as a first-line chemotherapeutic agent against colorectal
cancer (CRC), but drug resistance occurs frequently and significantly limits its clinical success. …
cancer (CRC), but drug resistance occurs frequently and significantly limits its clinical success. …
[HTML][HTML] Baicalin induces apoptosis and suppresses the cell cycle progression of lung cancer cells through downregulating Akt/mTOR signaling pathway
X Sui, X Han, P Chen, Q Wu, J Feng, T Duan… - Frontiers in Molecular …, 2021 - frontiersin.org
Baicalin, as a natural active ingredient extracted and isolated from the traditional Chinese
medicine Scutellaria baicalensis Georgi., has been potentially used in various areas for its …
medicine Scutellaria baicalensis Georgi., has been potentially used in various areas for its …
[HTML][HTML] β-Elemene reverses the resistance of p53-deficient colorectal cancer cells to 5-fluorouracil by inducing pro-death autophagy and cyclin D3-dependent cycle …
…, B Zhai, X Chen, W Wang, B Chen, X Han… - … in bioengineering and …, 2020 - frontiersin.org
Objective Colorectal cancer is a malignant tumor of the digestive system with high morbidity
and mortality. 5-fluorouracil remains a widely used chemotherapeutic drug in the treatment …
and mortality. 5-fluorouracil remains a widely used chemotherapeutic drug in the treatment …
[HTML][HTML] Genome-Wide Identification and Comprehensive Analysis of the AP2/ERF Gene Family in Pomegranate Fruit Development and Postharvest Preservation
R Wan, J Song, Z Lv, X Qi, X Han, Q Guo, S Wang… - Genes, 2022 - mdpi.com
Pomegranate (Punica granatum L.) is a kind of fruit with significant economic, ecological and
health values. AP2/ERF transcription factors belong to a large group of factors mainly found …
health values. AP2/ERF transcription factors belong to a large group of factors mainly found …
[HTML][HTML] p53/PCDH17/Beclin-1 proteins as prognostic predictors for urinary bladder cancer
L Chen, Y Liu, Q Zhang, M Zhang, X Han, Q Li… - Journal of …, 2019 - ncbi.nlm.nih.gov
Purpose: To determine whether p53, PCDH17, Beclin-1 expression is associated with
clinicopathological characteristics of bladder cancer. Materials and Methods: 75 patients with non-…
clinicopathological characteristics of bladder cancer. Materials and Methods: 75 patients with non-…
[HTML][HTML] Preparation, characterization, pharmacokinetics and anticancer effects of PEGylated β-elemene liposomes
B Zhai, Q Wu, W Wang, M Zhang, X Han… - Cancer biology & …, 2020 - ncbi.nlm.nih.gov
Objective: This study aimed to develop a new polyethylene glycol (PEG) ylated β-elemene
liposome (PEG-Lipo-β-E) and evaluate its characterization, pharmacokinetics, antitumor …
liposome (PEG-Lipo-β-E) and evaluate its characterization, pharmacokinetics, antitumor …