User profiles for Xinyao Qiu
 | Xinyao QiuDepartment of Economics, Stanford University Verified email at stanford.edu Cited by 24 |
Comprehensive analysis of spatial architecture in primary liver cancer
Heterogeneity is the major challenge for cancer prevention and therapy. Here, we first
constructed high-resolution spatial transcriptomes of primary liver cancers (PLCs) containing …
constructed high-resolution spatial transcriptomes of primary liver cancers (PLCs) containing …
M6A Demethylase ALKBH5 Regulates PD-L1 Expression and Tumor Immunoenvironment in Intrahepatic Cholangiocarcinoma
X Qiu, S Yang, S Wang, J Wu, B Zheng, K Wang… - Cancer Research, 2021 - AACR
This study identifies PD-L1 mRNA as a target of ALKBH5 and reveals a role for ALKBH5 in
regulating the tumor immune microenvironment and immunotherapy efficacy. …
regulating the tumor immune microenvironment and immunotherapy efficacy. …
Trajectory and Functional Analysis of PD‐1high CD4+CD8+ T Cells in Hepatocellular Carcinoma by Single‐Cell Cytometry and Transcriptome Sequencing
B Zheng, D Wang, X Qiu, G Luo, T Wu… - Advanced …, 2020 - Wiley Online Library
The spatial heterogeneity of immune microenvironment in hepatocellular carcinoma (HCC)
remains elusive. Here, a single‐cell study involving 17 432 600 immune cells of 39 matched …
remains elusive. Here, a single‐cell study involving 17 432 600 immune cells of 39 matched …
[HTML][HTML] Modulation of gut microbiota to enhance effect of checkpoint inhibitor immunotherapy
J Wu, S Wang, B Zheng, X Qiu, H Wang… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence demonstrated the crucial role of gut microbiota in many human
diseases, including cancer. Checkpoint inhibitor therapy has emerged as a novel treatment and …
diseases, including cancer. Checkpoint inhibitor therapy has emerged as a novel treatment and …
Hepatobiliary tumor organoids reveal HLA class I neoantigen landscape and antitumoral activity of neoantigen peptide enhanced with immune checkpoint inhibitors
…, Y Zhao, Y Zong, Y Zhang, S Yang, X Qiu… - Advanced …, 2022 - Wiley Online Library
Neoantigen‐directed therapy lacks preclinical models recapitulating neoantigen
characteristics of original tumors. It is urgent to develop a platform to assess T cell response for …
characteristics of original tumors. It is urgent to develop a platform to assess T cell response for …
[HTML][HTML] Integrated multi-omics landscape of liver metastases
…, L Qian, Z Li, Y Li, J Bai, B Zheng, K Chen, X Qiu… - Gastroenterology, 2023 - Elsevier
Background & Aims Lack of thorough knowledge about the complicated immune microenvironment
(IM) within a variety of liver metastases (LMs) leads to inappropriate treatment and …
(IM) within a variety of liver metastases (LMs) leads to inappropriate treatment and …
Discovery of a Carbamoyl Phosphate Synthetase 1–Deficient HCC Subtype With Therapeutic Potential Through Integrative Genomic and Experimental Analysis
…, J Wu, K Wang, Y Zhao, S Yang, S Wang, X Qiu… - …, 2021 - Wiley Online Library
Background and Aims Metabolic reprogramming plays an important role in tumorigenesis.
However, the metabolic types of different tumors are diverse and lack in‐depth study. Here, …
However, the metabolic types of different tumors are diverse and lack in‐depth study. Here, …
Family spillover effects of marginal diagnoses: The case of ADHD
The health care system commonly relies on information about family medical history in the
allocation of screenings and in diagnostic processes. At the same time, an emerging literature …
allocation of screenings and in diagnostic processes. At the same time, an emerging literature …
[HTML][HTML] The Wnt/β-catenin signaling pathway in the tumor microenvironment of hepatocellular carcinoma
K Wang, X Qiu, Y Zhao, H Wang… - Cancer Biology & …, 2022 - ncbi.nlm.nih.gov
The Wnt/β-catenin signaling pathway regulates many aspects of tumor biology, and many
studies have focused on the role of this signaling pathway in tumor cells. However, it is now …
studies have focused on the role of this signaling pathway in tumor cells. However, it is now …
[HTML][HTML] The identification and functional analysis of CD8+ PD-1+ CD161+ T cells in hepatocellular carcinoma
Z Li, B Zheng, X Qiu, R Wu, T Wu, S Yang, Y Zhu… - NPJ precision …, 2020 - nature.com
Immunotherapy is a powerful therapeutic strategy for end-stage hepatocellular carcinoma (HCC).
It is well known that T cells, including CD8+PD-1+ T cells, play important roles …
It is well known that T cells, including CD8+PD-1+ T cells, play important roles …