The Mitogen Activated Protein Kinase (MAPK) signaling plays a critical role in the outcome
and the sensitivity to anticancer therapies. Activated MAPK can transmit extracellular signals …

Ferroptosis is a newly discovered type of cell death triggered by intracellular phospholipid
peroxidation that is morphologically, biologically and genetically distinct from other types of …

Autophagy is an evolutionarily conserved process in eukaryotes that eliminates harmful
components and maintains cellular homeostasis in response to a series of extracellular insults. …

Ferroptosis is an iron-dependent, oxidative cell death, and is characterized by iron-dependent
accumulation of reactive oxygen species (ROS) within the cell. It has been implicated in …

Ferroptosis, a novel form of programmed cell death, is characterized by iron-dependent lipid
peroxidation and has been shown to be involved in multiple diseases, including cancer. …

Background and Purpose: RAS mutations limit the effectiveness of anti-epidermal growth factor
receptor (EGFR) monoclonal antibodies in combination with chemotherapy for metastatic …

The therapeutic limitations such as insufficient efficacy, drug resistance, metastasis, and
undesirable side effects are frequently caused by the long duration monotherapy based on …

The treatment of diabetic ulcer (DU) remains a major clinical challenge due to the complex
wound-healing milieu that features chronic wounds, impaired angiogenesis, persistent pain, …

Curcumenol, an effective ingredient of Wenyujin, has been reported that exerted its
antitumor potential in a few cancer types. However, the effect and molecular mechanism of …

… Xinbing Sui, Tian Xie, and Wei Tao guided and designed the research; Xiaying Chen and Na
… Xinbing Sui and Xiaying Chen wrote manuscript with contributions from the other authors. …