[HTML][HTML] The role of cytokines in predicting the response and adverse events related to immune checkpoint inhibitors
M Wang, X Zhai, J Li, J Guan, S Xu, YY Li… - Frontiers in …, 2021 - frontiersin.org
Recently, the overall survival (OS) and progression-free survival (PFS) of patients with
advanced cancer has been significantly improved due to the application of immune checkpoint …
advanced cancer has been significantly improved due to the application of immune checkpoint …
[HTML][HTML] The mechanism and risk factors for immune checkpoint inhibitor pneumonitis in non-small cell lung cancer patients
X Zhai, J Zhang, Y Tian, J Li, W Jing… - Cancer Biology & …, 2020 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are new and promising therapeutic agents for non-small
cell lung cancer (NSCLC). However, along with demonstrating remarkable efficacy, ICIs can …
cell lung cancer (NSCLC). However, along with demonstrating remarkable efficacy, ICIs can …
[HTML][HTML] Potential immune escape mechanisms underlying the distinct clinical outcome of immune checkpoint blockades in small cell lung cancer
Y Tian, X Zhai, A Han, H Zhu, J Yu - Journal of Hematology & Oncology, 2019 - Springer
Small cell lung cancer (SCLC) is one of the deadliest cancer types in the world. Despite the
high response rate to frontline platinum-containing doublets, relapse is inevitable for the …
high response rate to frontline platinum-containing doublets, relapse is inevitable for the …
Radiation therapy for extensive-stage small-cell lung cancer in the era of immunotherapy
Y Tian, J Ma, X Jing, X Zhai, Y Li, Z Guo, J Yu, H Zhu - Cancer Letters, 2022 - Elsevier
Unlike non-small-cell lung cancer (NSCLC), the progression of small-cell lung cancer (SCLC)
is slow. Extensive-stage SCLC (ES-SCLC) is a serious threat to human health, with a 5-…
is slow. Extensive-stage SCLC (ES-SCLC) is a serious threat to human health, with a 5-…
Clinical outcomes of immune checkpoint blockades and the underlying immune escape mechanisms in squamous and adenocarcinoma NSCLC
Y Tian, X Zhai, W Yan, H Zhu, J Yu - Cancer medicine, 2021 - Wiley Online Library
Immune checkpoint blockades (ICBs) have changed the standard of care of squamous and
adenocarcinoma non‐small cell lung cancer (NSCLC). Whereas detailed researches …
adenocarcinoma non‐small cell lung cancer (NSCLC). Whereas detailed researches …
Long non-coding RNA DQ786243 modulates the induction and function of CD4+ Treg cells through Foxp3-miR-146a-NF-κB axis: Implications for alleviating oral …
J Wang, X Zhai, J Guo, Y Li, Y Yang, L Wang… - International …, 2019 - Elsevier
The present study was aimed to investigate the effects of the long non-coding RNA
DQ786243 in the regulation of Treg cells in oral lichen planus (OLP), as well as to evaluate its …
DQ786243 in the regulation of Treg cells in oral lichen planus (OLP), as well as to evaluate its …
[HTML][HTML] Therapeutic effect of osimertinib plus cranial radiotherapy compared to osimertinib alone in NSCLC patients with EGFR-activating mutations and brain …
X Zhai, W Li, J Li, W Jia, W Jing, Y Tian, S Xu, Y Li… - Radiation …, 2021 - Springer
Background The study aimed to compare the efficacy of osimertinib plus cranial radiotherapy
(RT) with osimertinib alone in advanced non-small-cell lung cancer (NSCLC) patients …
(RT) with osimertinib alone in advanced non-small-cell lung cancer (NSCLC) patients …
[HTML][HTML] Downregulation of lncRNA XR_429159. 1 linked to brain metastasis in patients with limited-stage small-cell lung cancer
J Li, W Jing, W Jia, X Zhai, H Zhu, J Yu - Frontiers in Oncology, 2021 - frontiersin.org
Purpose: The purpose of this study was to identify aberrant long non-coding RNAs (lncRNAs)
and explore the predictive value of lncRNA expression patterns on the risk of brain …
and explore the predictive value of lncRNA expression patterns on the risk of brain …
Outcomes of first-line anti-PD-L1 blockades combined with brain radiotherapy for extensive-stage small-cell lung cancer with brain metastasis
J Ma, Y Tian, S Hao, L Zheng, W Hu, X Zhai… - Journal of Neuro …, 2022 - Springer
Introduction Anti-programmed cell death-ligand 1 (Anti-PD-L1) blockades have become the
first-line treatment of extensive-stage small-cell lung cancer (ES-SCLC) from CASPIAN and …
first-line treatment of extensive-stage small-cell lung cancer (ES-SCLC) from CASPIAN and …
[HTML][HTML] MTAP-deficiency could predict better treatment response in advanced lung adenocarcinoma patients initially treated with pemetrexed-platinum chemotherapy …
W Jing, H Zhu, W Liu, X Zhai, H Tian, J Yu - Scientific Reports, 2020 - nature.com
To investigate the predictive value of methylthioadenosine phosphorylase (MTAP) on
treatment response and survival in advanced lung adenocarcinoma. MTAP expression was …
treatment response and survival in advanced lung adenocarcinoma. MTAP expression was …