Synergy effects of herb extracts: pharmacokinetics and pharmacodynamic basis

Y Yang, Z Zhang, S Li, X Ye, X Li, K He - Fitoterapia, 2014 - Elsevier
Herbal medicine, especially traditional Chinese medicine and Ayurvedic medicine have
played and still play an important role in fighting against various diseases. Emerging clinical …

Carbon quantum dot-decorated TiO2 for fast and sustainable antibacterial properties under visible-light

Y Yan, W Kuang, L Shi, X Ye, Y Yang, X Xie… - Journal of Alloys and …, 2019 - Elsevier
This work demonstrates that the effective use of antimicrobial agents (CQDs-TiO 2 : carbon
quantum dot-decorated titanium dioxide) and natural resources, such as sunlight, is able to …

Evaluation of antidiabetic potential of selected traditional Chinese medicines in STZ-induced diabetic mice

K He, X Li, X Chen, X Ye, J Huang, Y Jin, P Li… - Journal of …, 2011 - Elsevier
AIMS: Traditional Chinese medicine (TCM) has been used for treating complex chronic
diseases owing to their fewer side-effects, better patient tolerance and relatively less cost. The …

The Hypoglycemic and Synergistic Effect of Loganin, Morroniside, and Ursolic Acid Isolated from the Fruits of Cornus officinalis

…, M Feng, D Wang, Y Wang, X Li, X Ye - Phytotherapy …, 2016 - Wiley Online Library
Hypoglycemic activity‐guided separation of ethanol extracts from the fruits of Cornus
officinalis Sieb. et Zucc (CO) led to the isolation of loganin, morroniside, and ursolic acid. The …

Enhanced oral bioavailability of silybin by a supersaturatable self-emulsifying drug delivery system (S-SEDDS)

Y Wei, X Ye, X Shang, X Peng, Q Bao, M Liu… - Colloids and Surfaces A …, 2012 - Elsevier
A high payload supersaturatable self-emulsifying drug delivery system (S-SEDDS) was
explored to improve the oral bioavailability of silybin, a poorly water-soluble drug candidate, …

[HTML][HTML] Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways

…, Z Zou, Y Xiao, Y Yang, M Feng, X Li, X Ye - … et Biophysica Acta (BBA …, 2016 - Elsevier
It is hypothesized that Rhizoma Coptidis (RC) alkaloids exert their hypolipidemic effects
primarily by targeting the gastrointestinal tract and liver. Thus, this study was conducted to …

Safety evaluation of main alkaloids from Rhizoma Coptidis

J Yi, X Ye, D Wang, K He, Y Yang, X Liu, X Li - Journal of …, 2013 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Rhizoma Coptidis (RC), a widely used traditional
Chinese medicine, has been used for the treatment of heat-clearing and detoxifying, but …

The anti-hyperglycemia effects of Rhizoma Coptidis alkaloids: A systematic review of modern pharmacological studies of the traditional herbal medicine

H Ma, K He, J Zhu, X Li, X Ye - Fitoterapia, 2019 - Elsevier
Hyperglycemia is a common endocrine system disease, which seriously affects people's
health with a increasing morbidity in recent years. Rhizoma Coptidis (RC), one of the most …

Saponin rich fractions from Polygonatum odoratum (Mill.) Druce with more potential hypoglycemic effects

Y Deng, K He, X Ye, X Chen, J Huang, X Li… - Journal of …, 2012 - Elsevier
AIMS: The root of Polygonatum odoratum (YuZhu), also a medicinal food has long been
used for the treatment of diabetes. The objective of the study was to characterize the anti-…

Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway

B Han, P Jiang, Z Li, Y Yu, T Huang, X Ye, X Li - Phytomedicine, 2018 - Elsevier
Background Colorectal cancer is the third leading cause of cancer-related deaths in the
word. Coptisine (COP), an isoquinoline alkaloid derived from Coptis chinensis Franch, …