Diagnosis of the Coronavirus disease (COVID-19): rRT-PCR or CT?

…, B Fan, C Wang, B Zeng, Z Li, X Li, H Li - European journal of …, 2020 - Elsevier
Purpose To evaluate the diagnostic value of computed tomography (CT) and real-time
reverse-transcriptase-polymerase chain reaction (rRT-PCR) for COVID-19 pneumonia. Methods …

A new support for the immobilization of penicillin acylase

J He, X Li, DG Evans, X Duan, C Li - Journal of Molecular Catalysis B …, 2000 - Elsevier
Mesoporous MCM-41 having well ordered long-range structure, large pore diameters, narrow
pore-size distribution, high pore volume and specific surface area has been synthesized. …

Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl …

X Shi, X Chen, X Li, X Lan, C Zhao, S Liu, H Huang… - Clinical Cancer …, 2014 - AACR
Purpose: Chronic myelogenous leukemia (CML) is characterized by the constitutive
activation of Bcr-Abl tyrosine kinase. Bcr-Abl-T315I is the predominant mutation that causes …

[HTML][HTML] Association between oxidative DNA damage and risk of colorectal cancer: sensitive determination of urinary 8-hydroxy-2′-deoxyguanosine by UPLC-MS/MS …

C Guo, X Li, R Wang, J Yu, M Ye, L Mao, S Zhang… - Scientific reports, 2016 - nature.com
Oxidative DNA damage plays crucial roles in the pathogenesis of numerous diseases including
cancer. 8-hydroxy-2′-deoxyguanosine (8-OHdG) is the most representative product of …

Intra-/inter-molecular synergistic inhibition effect of sulfonate surfactant and 2-benzothiazolethiol on carbon steel corrosion in 3.5% NaCl solution

H Zhu, X Li, X Lu, X Chen, J Li, X Han, X Ma, Z Hu - Corrosion Science, 2021 - Elsevier
A sulfonate surfactant (CHT) was synthesized, reacted with 2-benzothiazolethiol (MBT) to
obtain CHMT to investigate the intramolecular synergistic inhibition effect of CHT and MBT. …

Copper-dependent autophagic degradation of GPX4 drives ferroptosis

Q Xue, D Yan, X Chen, X Li, R Kang, DJ Klionsky… - Autophagy, 2023 - Taylor & Francis
Ferroptosis is a type of iron-dependent regulated cell death characterized by unrestricted lipid
peroxidation and membrane damage. Although GPX4 (glutathione peroxidase 4) plays a …

Nurses endured high risks of psychological problems under the epidemic of COVID-19 in a longitudinal study in Wuhan China

…, Z Liu, J Li, X Gong, J Liu, Z Wan, X Yuan, X Li… - Journal of psychiatric …, 2020 - Elsevier
Background Health care workers, especially frontline nurses, faced great challenges during
the coronavirus disease 2019 (COVID-19) outbreak. Aims To assess the magnitude of the …

[HTML][HTML] Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level

C Ye, L Qi, X Li, J Wang, J Yu, B Zhou, C Guo… - Cell Communication and …, 2020 - Springer
Background The role and mechanism of the nicotinamide adenine dinucleotide (NAD + )
salvage pathway in cancer cell proliferation is poorly understood. Nicotinamide …

[HTML][HTML] Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation

…, K Choi, K Smither, A Amegadzie, N Chen, X Li… - Nature …, 2023 - nature.com
Targeted protein degradation via “hijacking” of the ubiquitin-proteasome system using
proteolysis targeting chimeras (PROTACs) has evolved into a novel therapeutic modality. The …

[HTML][HTML] Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth

N Liu, X Li, H Huang, C Zhao, S Liao, C Yang, S Liu… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Proteasomes are attractive emerging targets for anti-cancer therapies. Auranofin (Aur), a
gold-containing compound clinically used to treat rheumatic arthritis, was recently approved by …