User profiles for Xiaobing Han

Xiaobing Han

LIESMARS, Wuhan University, China
Verified email at whu.edu.cn
Cited by 851

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

…, D Liu, ZJ Zhang, S Shan, X Han… - Proceedings of the …, 2000 - National Acad Sciences
Bcl-2 and related proteins are key regulators of apoptosis or programmed cell death
implicated in human disease including cancer. We recently showed that cell-permeable Bcl-2 …

[HTML][HTML] Pre-trained alexnet architecture with pyramid pooling and supervision for high spatial resolution remote sensing image scene classification

X Han, Y Zhong, L Cao, L Zhang - Remote Sensing, 2017 - mdpi.com
The rapid development of high spatial resolution (HSR) remote sensing imagery techniques
not only provide a considerable amount of datasets for scene classification tasks but also …

[HTML][HTML] An efficient and robust integrated geospatial object detection framework for high spatial resolution remote sensing imagery

X Han, Y Zhong, L Zhang - Remote Sensing, 2017 - mdpi.com
Geospatial object detection from high spatial resolution (HSR) remote sensing imagery is a
significant and challenging problem when further analyzing object-related information for …

A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12

…, D Deng, L Xi, W Lv, X Han, G Tao, L Yan, Z Han… - Nature …, 2013 - nature.com
To identify new genetic risk factors for cervical cancer, we conducted a genome-wide
association study in the Han Chinese population. The initial discovery set included 1,364 …

Multi-class geospatial object detection based on a position-sensitive balancing framework for high spatial resolution remote sensing imagery

Y Zhong, X Han, L Zhang - ISPRS journal of photogrammetry and remote …, 2018 - Elsevier
Multi-class geospatial object detection from high spatial resolution (HSR) remote sensing
imagery is attracting increasing attention in a wide range of object-related civil and …

Electronic and mechanical coupling in bent ZnO nanowires

X Han, L Kou, X Lang, J Xia, N Wang, R Qin… - Advanced …, 2009 - Wiley Online Library
Semiconductor nanowires (NWs) are currently attracting a great deal of interest as they are
expected to play an important role in the development of nanometer-scale technologies.[1] …

[HTML][HTML] Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines

…, X Fan, M Cayabyab, M Hiraoka, D Liu, X Han… - Journal of Biological …, 2002 - ASBMB
Chemokine receptor CXCR4 plays an important role in the immune system and the cellular
entry of human immunodeficiency virus type 1 (HIV-1). To probe the stereospecificity of the …

Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages

H Qiu, Y Fan, AG Joyee, S Wang, X Han… - The Journal of …, 2008 - journals.aai.org
Type I IFNs (IFNIs) have pleiotropic functions in regulating host innate and adaptive immune
responses to pathogens. To elucidate the role of IFNIs in host resistance to chlamydial …

HyNet: Hyper-scale object detection network framework for multiple spatial resolution remote sensing imagery

Z Zheng, Y Zhong, A Ma, X Han, J Zhao, Y Liu… - ISPRS Journal of …, 2020 - Elsevier
Faced with the problem of the large scale variation, geospatial object detection in multiple
spatial resolution (MSR) remote sensing imagery is a challenging task. To avoid the scale …

Structure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction

W Tian, X Han, M Yan, Y Xu, S Duggineni, N Lin… - Biochemistry, 2012 - ACS Publications
Overactivation or overexpression of β-catenin in the Wnt (wingless) signaling pathway plays
an important role in tumorigenesis. Interaction of β-catenin with T-cell factor (Tcf) DNA …