Peripheral T-cell lymphoma (PTCL) is a set of rare and highly heterogeneous group of
mature T-and NK-cell neoplasms associated with poor outcomes and lack of standard and …

RETINOIDS regulate many biological processes, including differen-tiation, morphogenesis
and cell proliferation 1–3 . They are also important therapeutic agents, but their clinical …

Retinoids have a broad spectrum of biological activities and are useful therapeutic agents.
Their physiological activities are mediated by two types of receptors, the retinoic acid …

The thermal and electrical conductivity of monolithic carbon aerogels was investigated at
room temperature. Results showed both the solid thermal conductivity and the electrical …

Background Tucidinostat (formerly known as chidamide) is an oral subtype-selective
histone deacetylase inhibitor. In an exploratory study, the combination of tucidinostat with …

Purpose Chidamide (CS055/HBI-8000) is a new histone deacetylase (HDAC) inhibitor of
the benzamide class currently under clinical development in cancer indications. This study …

Chiglitazar (Carfloglitazar) is a novel non-thiazolidinedione (TZD) structured peroxisome
proliferator-activated receptor (PPAR) pan-agonist that has shown promising effects on …

Purpose Chidamide (CS055/HBI-8000) is a new benzamide class of histone deacetylase
inhibitor with marked anti-tumor activity. This study reports the phase I results. Methods …

Histone deacetylase (HDAC) is one of the most characterized epigenetic modifiers, modulating
chromatin structure and gene expression, which plays an important role in cell cycle, …

Histone deacetylases (HDACs) play a critical role in gene transcription and have become a
novel target for the discovery of drugs against cancer and other diseases. During the past …