Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) is the most frequently mutated
oncogene, occurring in a variety of tumor types. Targeting KRAS mutations with drugs is …

In the past decades, various nanomaterials with unique properties have been explored for
bioapplications. Meanwhile, aptamers, generated from the systematic evolution of ligands by …

Demands for primary human hepatocytes are continuously increasing, while supply is
insufficient due to limited cell sources. To improve cell availability, the present study investigates …

Background Tongue images (the colour, size and shape of the tongue and the colour, thickness
and moisture content of the tongue coating), reflecting the health state of the whole body …

Gastric cancer (GC) is among the most lethal malignancies due to its poor early diagnosis
and high metastasis rate, and new therapeutic targets are urgently needed to develop …

The emergence of multidrug resistance (MDR) in malignant tumors is one of the leading threats
encountered currently in many chemotherapeutic agents. The overexpression of the ATP-…

Tumor-infiltrating T cells offer a promising avenue for cancer treatment, yet their states
remain to be fully characterized. Here we present a single-cell atlas of T cells from 308,048 …

Understanding tumor microenvironment (TME) reprogramming in gastric adenocarcinoma (GAC)
progression may uncover novel therapeutic targets. Here, we performed single-cell …

Variable refrigerant flow (VRF) systems are widely-adopted air conditioning systems. When
system faults occur in VRF systems, the efficiency of VRF system will drop drastically. This …

The tumor microenvironment (TME) has attracted attention owing to its essential role in tumor
initiation, progression, and metastasis. With the emergence of immunotherapies for various …