[HTML][HTML] Comprehensive transcriptome analysis identifies novel molecular subtypes and subtype-specific RNAs of triple-negative breast cancer
…, S Hao, J Wu, GY Liu, GH Di, DQ Li, XH He… - Breast Cancer …, 2016 - Springer
Background Triple-negative breast cancer (TNBC) is a highly heterogeneous group of cancers,
and molecular subtyping is necessary to better identify molecular-based therapies. While …
and molecular subtyping is necessary to better identify molecular-based therapies. While …
CXCR6 upregulation contributes to a proinflammatory tumor microenvironment that drives metastasis and poor patient outcomes in hepatocellular carcinoma
…, GM Shi, ZB Ding, YS Xiao, ZH Zhao, J Zhou, XH He… - Cancer research, 2012 - AACR
CXC chemokines and their cognate receptors have been implicated widely in cancer
pathogenesis. In this study, we report a critical causal relationship between CXCR6 expression …
pathogenesis. In this study, we report a critical causal relationship between CXCR6 expression …
[HTML][HTML] Integrative analyses identify osteopontin, LAMB3 and ITGB1 as critical pro-metastatic genes for lung cancer
Objective To explore the key regulatory genes associated with lung cancer in order to reduce
its occurrence and progress through silencing these key genes. Methods To identify the …
its occurrence and progress through silencing these key genes. Methods To identify the …
Activating mutations in PTPN3 promote cholangiocarcinoma cell proliferation and migration and are associated with tumor recurrence in patients
…, ZP Qiu, ZA Chen, ZF Zhang, SJ Qiu, J Zhou, XH He… - Gastroenterology, 2014 - Elsevier
Background & Aims The pathogenesis of intrahepatic cholangiocarcinoma (ICC), the second
most common hepatic cancer, is poorly understood, and the incidence of ICC is increasing …
most common hepatic cancer, is poorly understood, and the incidence of ICC is increasing …
The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation
Human endogenous retroviruses (HERVs) play pivotal roles in the development of breast
cancer. However, the detailed mechanisms of noncoding HERVs remain elusive. Here, our …
cancer. However, the detailed mechanisms of noncoding HERVs remain elusive. Here, our …
Arginine methylation of SIRT 7 couples glucose sensing with mitochondria biogenesis
…, YL Liang, QX Zhang, D Wang, MZ Lei, J Qu, XH He… - EMBO …, 2018 - embopress.org
Sirtuins ( SIRT s) are a class of lysine deacylases that regulate cellular metabolism and
energy homeostasis. Although sirtuins have been proposed to function in nutrient sensing and …
energy homeostasis. Although sirtuins have been proposed to function in nutrient sensing and …
Quantitative proteomic analysis identifies CPNE3 as a novel metastasis-promoting gene in NSCLC
…, Y Cui, X Liu, J Li, M Yan, L Liu, X He… - Journal of proteome …, 2013 - ACS Publications
To discover metastasis-associated proteins within cancer cells, we used the isobaric tags
for relative and absolute quantitation (iTRAQ) approach combined with nano liquid …
for relative and absolute quantitation (iTRAQ) approach combined with nano liquid …
[HTML][HTML] GNAI1 suppresses tumor cell migration and invasion and is post-transcriptionally regulated by Mir-320a/c/d in hepatocellular carcinoma
…, Y Zhang, J Ding, Q Tian, J Li, X He - Cancer biology & …, 2012 - ncbi.nlm.nih.gov
Objective To explore the role and regulation of guanine nucleotide-binding protein G (i), α-1
subunit (GNAI1) in hepatocellular carcinoma (HCC). Methods Expression of GNAI1 in HCC …
subunit (GNAI1) in hepatocellular carcinoma (HCC). Methods Expression of GNAI1 in HCC …
[HTML][HTML] Role of microRNAs in inflammation-associated liver cancer
L Huan, LH Liang, XH He - Cancer biology & medicine, 2016 - ncbi.nlm.nih.gov
Liver cancer, primarily hepatocellular carcinoma (HCC), is a major cause of cancer-related
death worldwide. HCC is a suitable model of inflammation-induced cancer because more …
death worldwide. HCC is a suitable model of inflammation-induced cancer because more …
[HTML][HTML] Macro-management of microRNAs in cell cycle progression of tumor cells and its implications in anti-cancer therapy
L Liang, X He - Acta Pharmacologica Sinica, 2011 - nature.com
The cell cycle, which is precisely controlled by a number of regulators, including cyclins and
cyclin-dependent kinases (CDKs), is crucial for the life cycle of mammals. Cell cycle …
cyclin-dependent kinases (CDKs), is crucial for the life cycle of mammals. Cell cycle …
