[HTML][HTML] m6A modification: recent advances, anticancer targeted drug discovery and beyond

LJ Deng, WQ Deng, SR Fan, MF Chen, M Qi, WY Lyu… - Molecular cancer, 2022 - Springer
Abnormal N6-methyladenosine (m6A) modification is closely associated with the occurrence,
development, progression and prognosis of cancer, and aberrant m6A regulators have …

[HTML][HTML] Exploring the relationship between hospital service quality, patient trust, and loyalty from a service encounter perspective in elderly with chronic diseases

AJ Shie, YF Huang, GY Li, WY Lyu, M Yang… - Frontiers in public …, 2022 - frontiersin.org
Based on the service encounter perspective, this study combines theoretical foundations for
such factors as service quality and the characteristics of the hospital service industry to …

Update on the synergistic effect of HSL and insulin in the treatment of metabolic disorders

YL Lan, JC Lou, W Lyu… - Therapeutic Advances in …, 2019 - journals.sagepub.com
Hormone-sensitive lipase (HSL) is one of the three lipases in adipose tissue present during
periods of energy demand. HSL is tightly controlled by insulin regulation via the central and …

Erianin inhibits the growth and metastasis through autophagy-dependent ferroptosis in KRASG13D colorectal cancer

Q Miao, W Deng, W Lyu, Z Sun, S Fan, M Qi… - Free Radical Biology …, 2023 - Elsevier
Colorectal cancer (CRC) is the third most common cause of cancer mortality worldwide.
Approximately 40% of CRC patients are KRAS sequence variation, including KRAS G13D …

Modeling SHANK3-associated autism spectrum disorder in Beagle dogs via CRISPR/Cas9 gene editing

R Tian, Y Li, H Zhao, W Lyu, J Zhao, X Wang, H Lu… - Molecular …, 2023 - nature.com
Despite intensive studies in modeling neuropsychiatric disorders especially autism spectrum
disorder (ASD) in animals, many challenges remain. Genetic mutant mice have contributed …

[HTML][HTML] Downregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent …

Y Lan, J Lou, J Hu, Z Yu, W Lyu… - Cancer biology & …, 2020 - ncbi.nlm.nih.gov
Objective: Temozolomide (TMZ) is commonly used for glioblastoma multiforme (GBM)
chemotherapy. However, drug resistance limits its therapeutic effect in GBM treatment. RNA-…

[HTML][HTML] Ginsenoside Rh2 augmented anti-PD-L1 immunotherapy by reinvigorating CD8+ T cells via increasing intratumoral CXCL10

MY Huang, YC Chen, WY Lyu, XY He, ZH Ye… - Pharmacological …, 2023 - Elsevier
Profiting from the sustained clinical improvement and prolonged patient survival, immune
checkpoint blockade of programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (…

Roles of the and in the process

WT Lyu, YH Lyu, MY Duan, DM Li, DY Chen, E Wang - Physical Review D, 2024 - APS
Motivated by the recent LHCb observations of T cs 0 (2900) 0 and T cs 0 (2900)++ in the
processes B 0→ D 0 D s+ π− and B+→ D− D s+ π+, we have investigated the decay B−→ D s+ …

Biochemical composition distribution in different grain layers is associated with the edible quality of rice cultivars

Z Ma, Y Wang, H Cheng, G Zhang, W Lyu - Food chemistry, 2020 - Elsevier
Clarifying the association of differences in endosperm biochemical composition with
nutrient and edible quality can guide rice breeding and cultivation. In this study, very-low-amylose-…

Directional conversion of a THz propagating wave into surface waves in deformable metagratings

J Liu, X Fang, F He, S Yin, W Lyu, H Geng, X Deng… - Optics …, 2021 - opg.optica.org
Controllable conversion between propagating light waves and surface waves (SWs) has
recently attracted significant research interests. This paper demonstrates, via numerical …