[HTML][HTML] ABC transporters and the hallmarks of cancer: roles in cancer aggressiveness beyond multidrug resistance

W Muriithi, LW Macharia, CP Heming… - Cancer Biology & …, 2020 - ncbi.nlm.nih.gov
The ATP-binding cassette transporters (ABC transporters) have been intensely studied over
the past 50 years for their involvement in the multidrug resistance (MDR) phenotype, …

[PDF][PDF] P-glycoprotein and cancer: what do we currently know?

CP Heming, W Muriithi, LW Macharia… - Heliyon, 2022 - cell.com
Acquired resistance during cancer treatment is unfortunately a frequent event. There are
several reasons for this, including the ability of the ATP-binding cassette transporters (ABC …

[HTML][HTML] The genotypic and phenotypic impact of hypoxia microenvironment on glioblastoma cell lines

LW Macharia, W Muriithi, CP Heming, DK Nyaga… - BMC cancer, 2021 - Springer
Background Glioblastoma is a fatal brain tumour with a poor patient survival outcome. Hypoxia
has been shown to reprogram cells towards a stem cell phenotype associated with self-…

[HTML][HTML] Evaluation of MiRNA Expression in Glioblastoma Stem-Like Cells: A Comparison between Normoxia and Hypoxia Microenvironment

LW Macharia, W Muriithi, DK Nyaga… - Onco, 2022 - mdpi.com
Purpose: Glioblastoma is an aggressive and incurable brain tumor whose progression is driven
in part by glioblastoma stem cells, which are also responsible for the tumor’s low therapy …

[PDF][PDF] Student's motives for utilizing social networking sites in private universities in Dar Es salaam, Tanzania

MK Muriithi, IW Muriithi - Academic Research International, 2013 - savap.org.pk
This study explored the student motives for utilizing SNSs in Dar Salaam Tanzania. The
Research design used in this study was cross-sectional Descriptive research design. The target …

[PDF][PDF] Factors influencing information and communication technology adoption among secondary school teachers in rural areas of Tanzania

MI Wanjiru, P Ssemaluulu, C Umeziirwete… - Internatonal Journal of …, 2022 - ijssit.com
Globally, the role of ICT is critical to successful teaching and learning. The realization of
educational innovations depends chiefly on the skills and knowledge of teachers. Research …

[PDF][PDF] Effects of financial literacy on the growth of micro enterprises funded by Uwezo fund in Nairobi County, Kenya

JW Muriithi - 2020 - su-plus.strathmore.edu
The need for financial literacy by micro enterprises has been emphasized by different
scholars. Financial literacy is the mastery of a set of knowledge, attitudes and behaviors. The …

P-glycoprotein and cancer: what do we currently know?

CP Heming, W Muriithi, LW Macharia… - molecules - europepmc.org
Acquired resistance during cancer treatment is unfortunately a frequent event. There are
several reasons for this, including the ability of the ATP-binding cassette transporters (ABC …

Effect of Nitrogen, Silicon, Rice By-product and Fungicide for Management of Rice Blast Disease in Mwea Irrigation Scheme of Kenya Catherine

CW Muriithi - 2014 - ir.jkuat.ac.ke
Rice (Oryza sativa L) is a staple food for nearly-half of the world population contributing over
20% of total world calorie intake. In Kenya it is the third most important cereal after maize …

[HTML][HTML] MicroRNAs, hypoxia and the stem-like state as contributors to cancer aggressiveness

LW Macharia, CM Wanjiru, MW Mureithi… - Frontiers in …, 2019 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNA molecules that play key regulatory roles in
cancer acting as both oncogenes and tumor suppressors. Due to their potential roles in …