BRCA1, a breast and ovarian tumor suppressor, colocalizes with markers of the inactive X
chromosome (Xi) on Xi in female somatic cells and associates with XIST RNA, as detected by …

BRCA1 is a central component of the DNA damage response mechanism and defects in
BRCA1 confer sensitivity to a broad range of DNA damaging agents. BRCA1 is required for …

The breast and ovarian cancer susceptibility genes, BRCA1and BRCA2, are likely to participate
in DNA lesion processing. Oxidative lesions, such as 8-oxoguanine, occur in DNA after …

There is now evidence to suggest that BRCA1 and BRCA2 are involved in the response of
cells to DNA damage and cell cycle checkpoint control. This report examines the death …

BRCA1 plays an important role in mechanisms of response to double-strand breaks,
participating in genome surveillance, DNA repair, and cell cycle checkpoint arrests. Here, we …

Human adenovirus (HAV) serotypes 2 and 5 are commonly used as vector backbones for
adenovirus-mediated gene transfer. However, HAVs were chosen as a backbone for the …

Satellite cells (SCs) are adult muscle stem cells that are mobilized when muscle homeostasis
is perturbed. Here, we show that serum response factor (Srf) is needed for optimal SC-…

Growth factor independence-1B (Gfi-1B) is a transcriptional repressor essential for erythropoiesis
and megakaryopoiesis. Targeted gene disruption of GFI1B in mice leads to embryonic …

The loss of BRCA1 function appears as an essential step in breast and ovarian epithelial
cells oncogenesis and is consistent with the concept that BRCA1 acts as a tumor suppressor …

Citrulline (Cit) actions on muscle metabolism remain unclear. Those latter were investigated
using a proteomic approach on Tibialis muscles from male Sprague‐Dawley rats. At 23 …