Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia
are important factors both in aging and in the development of cancer. Insulin/insulin-like …

The effect of the pineal indole hormone melatonin on the life span of mice, rats and fruit flies
has been studied using various approaches. It has been observed that in female CBA, SHR, …

Abstract Information obtained from animal models (mostly mice and rats) has contributed
substantially to the development of treatments for human cancers. However, important …

The Working Group concluded there was limited evidence that night shift work causes breast,
prostate, and colorectal cancer. This evaluation was based on comprehensive searches of …

At present, light pollution (exposure to light-at-night) both in the form of occupational exposure
during night work and as a personal choice and life style, is experienced by numerous …

Light-at-night has become an increasing and essential part of the modern lifestyle and
leads to a number of health problems, including excessive body mass index, cardiovascular …

The results of studies on the effect of pineal indole hormone melatonin on the life span of
mice, rats, fruit flies, and worms are critically reviewed. In mice, long-term administration of …

The role of the modulation of the pineal gland function in development of breast cancer is
discussed in this review. An inhibition of the pineal function with pinealectomy or with the …

Antioxidants specifically addressed to mitochondria have been studied to determine if they
can decelerate senescence of organisms. For this purpose, a project has been established …

Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are
important factors both in aging and in the development of cancer. It is possible that the life-…