Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography

JG Tjuvajev, N Avril, T Oku, T Sasajima, T Miyagawa… - Cancer research, 1998 - AACR
We report a series of studies that assess the feasibility and sensitivity of imaging of herpes
virus type one thymidine kinase (HSV1-tk) gene transfer and expression with [ 124 I]-5-iodo-2…

Tumor growth modulation by sense and antisense vascular endothelial growth factor gene expression: effects on angiogenesis, vascular permeability, blood volume …

T Oku, JG Tjuvajev, T Miyagawa, T Sasajima, A Joshi… - Cancer research, 1998 - AACR
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor, has
been investigated as a potent mediator of brain tumor angiogenesis and tumor growth. We …

Perfusion and metabolism in predicting the survival of patients with cerebral gliomas

K Mineura, T Sasajima, M Kowada, T Ogawa… - Cancer, 1994 - Wiley Online Library
Background. Noninvasive measurements of cerebral circulation and metabolism may be useful
for diagnosis in patients with brain tumors. The authors tested the prognostic significance …

Simultaneous microscopic and endoscopic monitoring during surgery for internal carotid artery aneurysms

…, T Ohta, Y Hirano, T Sugawara, T Sasajima… - Journal of …, 2004 - thejns.org
Object. The authors of this study evaluated the efficacy of simultaneous microscopic and
endoscopic monitoring during surgery for internal carotid artery (ICA) aneurysms. Methods. The …

Rapid immunohistochemistry based on alternating current electric field for intraoperative diagnosis of brain tumors

M Tanino, T Sasajima, H Nanjo, S Akesaka… - Brain tumor …, 2015 - Springer
Rapid immunohistochemistry (R-IHC) can contribute to the intraoperative diagnosis of central
nervous system (CNS) tumors. We have recently developed a new IHC method based on …

Trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid (anti-18F-FACBC) is a feasible alternative to 11C-methyl-L-methionine and magnetic resonance imaging for …

T Sasajima, T Ono, N Shimada, Y Doi, S Oka… - Nuclear medicine and …, 2013 - Elsevier
Introduction Amino acid PET tracers are promising for visualizing gliomas and evaluating
radiochemotherapeutic effects. We compared the glioma detection and early response …

Innovative approach in the diagnosis of gliomatosis cerebri using carbon-11-L-methionine positron emission tomography.

K Mineura, T Sasajima, M Kowada… - Journal of Nuclear …, 1991 - europepmc.org
A case of gliomatosis cerebri was studied with positron emission tomography (PET). Carbon-11-L-methionine
(11C-Met) accumulated in the diffusely infiltrative tumorous area more …

Anterior paraclinoid aneurysms

…, N Yanagida, S Mikawa, A Suzuki, T Sasajima… - Journal of …, 2002 - thejns.org
Object. The characteristics of a previously unclassified paraclinoid aneurysm arising from
the anterolateral (dorsal) wall of the proximal internal carotid artery were retrospectively …

Association of stem cell marker CD133 expression with dissemination of glioblastomas

A Sato, K Sakurada, T Kumabe, T Sasajima… - Neurosurgical …, 2010 - Springer
Dissemination of glioblastoma was once considered rare but is now increasingly encountered
with longer survival of glioblastoma patients. Despite the potential negative impact of …

Proliferation-dependent changes in amino acid transport and glucose metabolism in glioma cell lines

T Sasajima, T Miyagawa, T Oku, JG Gelovani… - European journal of …, 2004 - Springer
Amino acid imaging is increasingly being used for assessment of brain tumor malignancy,
extent of disease, and prognosis. This study explores the relationship between proliferative …