Background and Purpose— Blood pressure variability (BPV) may be an important prognostic
factor acutely after stroke. This review investigated the existing evidence for the effect of …

Background: The incidence of dementia is projected to rise over the coming decades, but
with no sensitive diagnostic tests available. Vascular pathology precedes the deposition of …

Background Whether rapid lowering of elevated blood pressure would improve the outcome
in patients with intracerebral hemorrhage is not known. Methods We randomly assigned …

Cardiovascular autonomic dysfunction in uremia. Cardiovascular morbidity and mortality is
common in chronic renal failure patients, and may be explained in part by abnormalities in …

Background Raised blood pressure is common after acute stroke and is associated with an
adverse prognosis. We sought to assess the feasibility, safety, and effects of two regimens for …

Background Thrombolytic therapy for acute ischemic stroke with a lower-than-standard dose
of intravenous alteplase may improve recovery along with a reduced risk of intracerebral …

Background Tranexamic acid can prevent death due to bleeding after trauma and post-partum
haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …

Background The optimum systolic blood pressure after endovascular thrombectomy for
acute ischaemic stroke is uncertain. We aimed to compare the safety and efficacy of blood …

Background Systolic blood pressure of more than 185 mm Hg is a contraindication to
thrombolytic treatment with intravenous alteplase in patients with acute ischaemic stroke, but the …

Background Asundexian (Bayer AG, Leverkusen, Germany), an oral small molecule factor XIa
(FXIa) inhibitor, might prevent thrombosis without increasing bleeding. Asundexian's effect …