Small protein domains, capable of specific binding to different target proteins have been
selected using combinatorial approaches. These binding proteins, called affibodies, were …

Affibody molecules are a class of engineered affinity proteins with proven potential for
therapeutic, diagnostic and biotechnological applications. Affibody molecules are small (6.5kDa) …

Genetic engineering enables the construction of gene man Genome Project (5), efficient
and robust production and purification strategies are necessary (6). For fusions resulting in …

The detection of cell-bound proteins that are produced due to aberrant gene expression in
malignant tumors can provide important diagnostic information influencing patient …

According to the amyloid hypothesis, the pathogenesis of Alzheimer's disease is triggered
by the oligomerization and aggregation of the amyloid-β (Aβ) peptide into protein plaques. …

Affibody® (affibody) ligands that are specific for the extracellular domain of human epidermal
growth factor receptor 2 (HER2/neu) have been selected by phage display technology from …

Display of heterologous proteins on the surface of microorganisms, enabled by means of
recombinant DNA technology, has become an increasingly used strategy in various …

Affibody molecules are small (6.5-kDa) affinity proteins based on a three-helix bundle
domain framework. Since their introduction 20 years ago as an alternative to antibodies for …

Genetic strategies have been used for more than two decades to improve bacterial
bioprocesses and to simplify recovery procedures. Such strategies include the design of efficient …

The first scientific attempts to control an infectious disease can be attributed to Edward
Jenner, who, in 1796 inoculated an 8-year-old boy with cowpox (vaccinia), giving the boy …