The genetic and phenotypic spectra of adult genetic leukoencephalopathies in a cohort of 309 patients

C Wu, M Wang, X Wang, W Li, S Li, B Chen, S Niu… - Brain, 2023 - academic.oup.com
Genetic leukoencephalopathies (gLEs) are a highly heterogeneous group of rare genetic
disorders. The spectrum of gLEs varies among patients of different ages. Distinct from the …

A class of amide ligands enable Cu-catalyzed coupling of (hetero) aryl halides with sulfinic acid salts under mild conditions

J Zhao, S Niu, X Jiang, Y Jiang, X Zhang… - The Journal of …, 2018 - ACS Publications
The amide derived from 4-hydroxy-l-proline and 2,6-dimethylaniline is a powerful ligand for
Cu-catalyzed coupling of (hetero)aryl halides with sulfinic acid salts, allowing the formation …

Clinical features and classification of neuronal Intranuclear inclusion disease

…, Y Pan, K Li, G Zhao, M Wang, G Wu, S Niu… - Neurology …, 2023 - AAN Enterprises
Background and Objectives Neuronal intranuclear inclusion body disease (NIID) is a
neurodegenerative disease with highly heterogeneous clinical manifestations. The present study …

c‐Myc mediated upregulation of long noncoding RNA SNHG12 regulates proliferation and drug sensitivity in natural killer/T‐cell lymphoma

…, J Wu, X Wang, F Wang, X Li, S Niu… - Journal of cellular …, 2019 - Wiley Online Library
Nasal‐type natural killer/T‐cell lymphoma (NKTCL) is an aggressive malignancy with poor
outcomes. The treatment of NKTCL requires intensive chemotherapy. Long noncoding RNAs (…

Pd-Catalyzed Dimethylation of Tyrosine-Derived Picolinamide for Synthesis of (S)-N-Boc-2,6-dimethyltyrosine and Its Analogues

X Wang, S Niu, L Xu, C Zhang, L Meng, X Zhang… - Organic …, 2017 - ACS Publications
A short and efficient synthesis of (S)-N-Boc-2,6-dimethyltyrosine utilizing palladium-catalyzed
directed C–H functionalization is described. This represents the first general method for the …

Novel mutations in HTRA1‐related cerebral small vessel disease and comparison with CADASIL

…, H Zheng, X Li, S Li, W Li, Z Wang, S Niu… - Annals of Clinical …, 2022 - Wiley Online Library
Objective There is evidence showing both heterozygous HTRA1 and homozygous HTRA1
mutations as causal for familial cerebral small vessel disease (CSVD). The clinical and …

[HTML][HTML] Clinical features and genetic spectrum of patients with clinically suspected hereditary progressive spastic paraplegia

Y Shi, A Wang, B Chen, X Wang, S Niu, W Li… - Frontiers in …, 2022 - frontiersin.org
Background and Purpose A variety of hereditary diseases overlap with neurological
phenotypes or even share genes with hereditary spastic paraplegia (HSP). The aim of this study …

[HTML][HTML] TIPE2 suppresses progression and tumorigenesis of esophageal carcinoma via inhibition of the Wnt/β-catenin pathway

…, Z Li, Z Sun, J Wu, X Wang, F Wang, X Li, S Niu… - Journal of Translational …, 2018 - Springer
Background Esophageal carcinoma is the eighth prevalent malignancy and ranks the sixth
in carcinoma-related death worldwide. Tumor necrosis factor-α-induced protein-8 like-2 (…

Orelabrutinib-bruton tyrosine kinase inhibitor-based regimens in the treatment of central nervous system lymphoma: a retrospective study

…, M Dong, SS Ma, XD Zhang, LN Zhu, ST Niu… - Investigational New …, 2022 - Springer
Background. Central nervous system lymphoma (CNSL) is an aggressive lymphoma.
Orelabrutinib, an oral Bruton tyrosine kinase inhibitor, is a new treatment strategy for CNSL. This …

A New Class of Amide Ligands Enable Cu‐Catalyzed Coupling of Sodium Methanesulfinate with (Hetero) aryl Chlorides

D Ma, S Niu, J Zhao, X Jiang, Y Jiang… - Chinese Journal of …, 2017 - Wiley Online Library
((2S,4R)‐4‐Hydroxy‐N‐(2‐methylnaphthalen‐1‐yl)pyrrolidine‐2‐carboxamide (HMNPC), an
amide derived from 4‐hydroxy‐L‐proline and 2‐methyl naphthalen‐1‐amine, is a powerful …