Purpose Inflammatory breast cancer (IBC) is one of the most aggressive forms of breast
cancer. Lapatinib, an oral reversible inhibitor of epidermal growth factor receptor (EGFR) and …

BACKGROUND Tumor necrosis factor‐α (TNF‐α) and stress proteins (heat shock proteins)
are determining factors in the immune response to tumor cells. The authors designated a …

BACKGROUND Tumor necrosis factors (TNFs) and heat shock protein 70 (hsp70) are
determining factors in immunologic mechanisms to tumor cells. The authors designed a case‐…

Background Leptin (LEP) has been consistently associated with angiogenesis and tumor
growth. Leptin exerts its physiological action through its specific receptor (LEPR). We have …

Several studies have shown statistical evidence of association between nasopharyngeal
carcinoma (NPC) and specific human leukocyte antigen (HLA) alleles and highlighted the …

Objectives. Interleukin-1 (IL-1) and interleukin-6 (IL-6) are determining factors in the immune
and inflammatory responses to tumors cells. Experimental data suggest that interleukin-1 …

Germ-line mutations in BRCA1 breast cancer susceptibility gene account for a large proportion
of hereditary breast cancer families and show considerable ethnic and geographical …

Interleukin-8 (IL-8), a potent chemoattractant, has been demonstrated to contribute to
human cancer progression through its potential functions as a mitogenic, angiogenic, and …

Background Sentinel lymph node biopsy (SLNB) demonstrates promising results as an
accurate alternative to axillary lymph node dissection in patients with locally advanced breast …

Background Xenobiotic Metabolizing Enzymes (XMEs) contribute to the detoxification of
numerous cancer therapy-induced products. This study investigated the susceptibility and …