Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a disease characterized
by chronic, profound, disabling, and unexplained fatigue. Although it is hypothesized that …

The purpose of this study was to determine the safety, distribution, internal dosimetry, and
initial human epidermal growth factor receptor 2 (HER2)–positive tumor images of 64 Cu-…

Aromatase, an enzyme that converts androgens to estrogens, has been reported to be involved
in several brain functions, including synaptic plasticity, neurogenesis, neuroprotection, …

P-glycoprotein (P-gp) plays a pivotal role in limiting the penetration of xenobiotic compounds
into the brain at the blood–brain barrier (BBB), where its expression increases with …

Although various noninvasive methods have been used to detect vasospasm, none of them
are sensitive enough for patients with sporadic attacks. Because abnormal fatty acid …

There is a strong potential demand for high-sensitivity and low-cost brain positron emission
tomography (PET) imaging that is applicable to early diagnosis of Alzheimer's disease. …

We examined cardiac neuronal function and β-receptor with a dual-tracer method of [ 131 I]meta-iodobenzylguanidine
(MIBG) and [ 125 I]iodocyanopindolol (ICYP) in rat heart failure …

Metaiodobenzylguanidine (MIBG) is a reliable marker for the detection of cardiac
adrenergic neuronal damage in heart failure. The cardioprotective properties of carvedilol, a …

317 Objectives There is a potential demand for compact, high-sensitivity, high-resolution, and
low-cost PET scanners in brain imaging such as for early diagnosis of Alzheimer’s disease…

Abnormalities in energy metabolism may play an important role in the development of
hypertensive heart failure. However, the transition from compensated hypertrophy to heart failure …