Multimaterial 3D and 4D bioprinting of heterogenous constructs for tissue engineering
Additive manufacturing (AM), which is based on the principle of layer‐by‐layer shaping and
stacking of discrete materials, has shown significant benefits in the fabrication of …
stacking of discrete materials, has shown significant benefits in the fabrication of …
[HTML][HTML] Open chromatin interaction maps reveal functional regulatory elements and chromatin architecture variations during wheat evolution
J Yuan, H Sun, Y Wang, L Li, S Chen, W Jiao, G Jia… - Genome Biology, 2022 - Springer
Background Bread wheat (Triticum aestivum) is an allohexaploid that is generated by two
subsequent allopolyploidization events. The large genome size (16 Gb) and polyploid …
subsequent allopolyploidization events. The large genome size (16 Gb) and polyploid …
[HTML][HTML] Artificial intelligence-assisted score analysis for predicting the expression of the immunotherapy biomarker PD-L1 in lung cancer
…, F Zhang, Y Xing, X Hu, H Zhang, S Chen… - Frontiers in …, 2022 - frontiersin.org
Programmed cell death ligand 1 (PD-L1) is a critical biomarker for predicting the response
to immunotherapy. However, traditional quantitative evaluation of PD-L1 expression using …
to immunotherapy. However, traditional quantitative evaluation of PD-L1 expression using …
MicroRNA-451 negatively regulates hepatic glucose production and glucose homeostasis by targeting glycerol kinase–mediated gluconeogenesis
S Zhuo, M Yang, Y Zhao, X Chen, F Zhang, N Li… - Diabetes, 2016 - Am Diabetes Assoc
MicroRNAs (miRNAs) are a new class of regulatory molecules implicated in type 2 diabetes,
which is characterized by insulin resistance and hepatic glucose overproduction. We show …
which is characterized by insulin resistance and hepatic glucose overproduction. We show …
[HTML][HTML] Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver
S Zhong, L Li, N Liang, L Zhang, X Xu, S Chen, H Yin - Redox Biology, 2021 - Elsevier
HMG-CoA reductase (HMGCR) is the rate-limiting enzyme in cholesterol biosynthesis and
the target for cholesterol-lowering therapy. Acetaldehyde dehydrogenase 2 (ALDH2) is …
the target for cholesterol-lowering therapy. Acetaldehyde dehydrogenase 2 (ALDH2) is …
[HTML][HTML] How well does the ERA5 reanalysis capture the extreme climate events over China? Part I: Extreme precipitation
X Lei, W Xu, S Chen, T Yu, Z Hu, M Zhang… - Frontiers in …, 2022 - frontiersin.org
ERA5 is the fifth-generation atmospheric reanalysis of the European Center for Medium-Range
Weather Forecasts, with high spatiotemporal resolution and global coverage. However, …
Weather Forecasts, with high spatiotemporal resolution and global coverage. However, …
Asymmetric variation in DNA methylation during domestication and de-domestication of rice
S Cao, K Chen, K Lu, S Chen, X Zhang, C Shen… - The Plant …, 2023 - academic.oup.com
Hundreds of plant species have been domesticated to feed human civilization, while some
crops have undergone de-domestication into agricultural weeds, threatening global food …
crops have undergone de-domestication into agricultural weeds, threatening global food …
Fpr2 deficiency alleviates diet-induced insulin resistance through reducing body weight gain and inhibiting inflammation mediated by macrophage chemotaxis and M1 …
X Chen, S Zhuo, T Zhu, P Yao, M Yang, H Mei, N Li… - Diabetes, 2019 - Am Diabetes Assoc
Obesity and related inflammation are critical for the pathogenesis of insulin resistance, but
the underlying mechanisms are not fully understood. Formyl peptide receptor 2 (FPR2) plays …
the underlying mechanisms are not fully understood. Formyl peptide receptor 2 (FPR2) plays …
[HTML][HTML] How well does the ERA5 reanalysis capture the extreme climate events over China? Part II: Extreme temperature
W Xu, X Lei, S Chen, T Yu, Z Hu, M Zhang… - Frontiers in …, 2022 - frontiersin.org
The fifth-generation atmospheric reanalysis of the European Center for Medium-Range
Weather Forecasts (ERA5) is the latest reanalysis product. ERA5 has wider assimilation data …
Weather Forecasts (ERA5) is the latest reanalysis product. ERA5 has wider assimilation data …
Fructose‐1, 6‐bisphosphate aldolase B depletion promotes hepatocellular carcinogenesis through activating insulin receptor signaling and lipogenesis
…, X Shen, L Zhang, J Lv, Y Wang, H Jiang, S Chen… - …, 2021 - Wiley Online Library
Background and Aims Insulin receptor (IR) transduces cell surface signal through
phosphoinositide 3‐kinase (PI3K)–AKT pathways or translocates to the nucleus and binds to the …
phosphoinositide 3‐kinase (PI3K)–AKT pathways or translocates to the nucleus and binds to the …