The BRCA1 gene was identified and cloned in 1994 based its linkage to early onset breast
cancer and breast‐ovarian cancer syndromes in women. While inherited mutations of …

Studies increasingly indicate that dietary indole-3-carbinol (I3C) prevents the development
of estrogen-enhanced cancers including breast, endometrial and cervical cancers. …

BRCA1, a tumor suppressor gene on chromosome 17q21, was identified in 1994 based on
its linkage to hereditary breast and ovarian cancer syndromes. The BRCA1 gene encodes a …

In the present study, we report the characterization of the p53 tumor suppressor pathway in
the 60 cell lines of the National Cancer Institute (NCI) anticancer drug screen, as well as …

Exposure of mammalian cells to ionizing radiation (IR) induces a complex array of cellular
responses including cell cycle arrest and/or apoptosis. IR-induced G 1 arrest has been shown …

DOI: 10.1002/adma. 201400866 properties as that of a polypeptide comprising of several
GSH molecules, and this class of materials have been shown to have good biocompatibility in …

The possibility that appropriately designed chemotherapy could act selectively against p53-defective
tumor cells was explored in MCF-7 human breast cancer cells. These cells were …

Background: Arrest of the cell cycle in G 2 phase following DNA damage helps protect cell
viability by allowing time for DNA repair before entry into mitosis (M phase). Abrogation of G 2 …

Graphene quantum dots (GQD) generate intrinsic fluorescence, and improves aqueous
stability of graphene oxide (GO) while maintaining wide chemical adaptability and high …

A new type of metabolizable and efficient radiosensitizers for cancer radiotherapy is
presented by combining ultrasmall Au nanoclusters (NCs, <2 nm) with biocompatible coating …