The Ca2+‐activated Cl channel, ANO1 (TMEM16A), is a double‐edged sword in cell proliferation and tumorigenesis

Z Qu, W Yao, R Yao, X Liu, K Yu, C Hartzell - Cancer medicine, 2014 - Wiley Online Library
Since anoctamin 1 ANO 1 ( TMEM 16A) was found to be a molecular component of Ca 2+ ‐activated
Cl − channels, its role in tumorigenesis has gained attention at a fast pace. ANO 1 …

MiR‐200b expression in breast cancer: a prognostic marker and act on cell proliferation and apoptosis by targeting Sp1

YS Yao, J Hu, Z Shen, RY Yao, SH Liu… - Journal of cellular …, 2015 - Wiley Online Library
Micro RNA s (mi RNA s) have been identified as important post‐transcriptional regulators
involved in various biological and pathological processes of cells. In the present study, we …

The miR‐3127‐5p/p‐STAT 3 axis up‐regulates PD‐L1 inducing chemoresistance in non‐small‐cell lung cancer

D Tang, D Zhao, Y Wu, R Yao, L Zhou… - Journal of cellular …, 2018 - Wiley Online Library
It is less known about mi RNA 3127‐5p induced up‐regulation of PD ‐L1, immune escape
and drug resistance caused by increased PD ‐L1 in lung cancer. In this study, lentivirus was …

[HTML][HTML] The tumor suppressor miR-124 inhibits cell proliferation by targeting STAT3 and functions as a prognostic marker for postoperative NSCLC patients

…, Y Li, S Liu, C Gao, X Hou, R Yao… - … journal of oncology, 2015 - spandidos-publications.com
The aim of the present study was to investigate the role of miR-124 in lung cancer and
identify the potential predictive value of miR-124 in postoperative non-small cell lung cancer (…

FOXM1 mediates resistance to docetaxel in gastric cancer via up‐regulating Stathmin

X Li, R Yao, L Yue, W Qiu, W Qi, S Liu… - Journal of cellular …, 2014 - Wiley Online Library
Docetaxel is commonly used as an effective chemotherapeutic drug for gastric cancer patients
recently. With the increasing emergence of docetaxel resistance nowadays, identification …

CRM1 is a novel independent prognostic factor for the poor prognosis of gastric carcinomas

F Zhou, W Qiu, R Yao, J Xiang, X Sun, S Liu, J Lv… - Medical oncology, 2013 - Springer
Gastric cancer (GC) is a highly aggressive malignant tumor. Its high mortality rate prompts
the urgent need for novel therapeutic agents. The aim of this study is to detect the expression …

[HTML][HTML] Characterization of an alkaline alginate lyase with pH-stable and thermo-tolerance property

…, X Chen, X Bi, Y Ren, Q Han, Y Zhou, Y Han, R Yao… - Marine drugs, 2019 - mdpi.com
Alginate oligosaccharides (AOS) show versatile bioactivities. Although various alginate lyases
have been characterized, enzymes with special characteristics are still rare. In this study, …

[HTML][HTML] P53 prevent tumor invasion and metastasis by down-regulating IDO in lung cancer

D Tang, L Yue, R Yao, L Zhou, Y Yang, L Lu, W Gao - Oncotarget, 2017 - ncbi.nlm.nih.gov
In present study, we are to clear demonstrate the genetic evidence of IDO signaling's impact
on invasion and metastasis in lung cancer. Here we examined IDO1 expression levels in …

[HTML][HTML] The role and mechanisms of gut microbiota in diabetic nephropathy, diabetic retinopathy and cardiovascular diseases

Q Lv, Z Li, A Sui, X Yang, Y Han, R Yao - Frontiers in Microbiology, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM) and T2DM-related complications [such as retinopathy,
nephropathy, and cardiovascular diseases (CVDs)] are the most prevalent metabolic diseases. …

[HTML][HTML] The role of the mitochondrial calcium uniporter in cerebral ischemia/reperfusion injury in rats involves regulation of mitochondrial energy metabolism

…, P Wang, S Li, Y Guo, R Yao - Molecular …, 2013 - spandidos-publications.com
The mitochondrial calcium uniporter (MCU) maintains intracellular Ca2+ homeostasis by
transporting Ca2+ from the cell cytosol into the mitochondrial matrix and is important for …