[HTML][HTML] Phase 1b study of sintilimab plus anlotinib as first-line therapy in patients with advanced NSCLC

T Chu, R Zhong, H Zhong, BO Zhang, W Zhang… - Journal of Thoracic …, 2021 - Elsevier
Introduction Although the interaction between tumor immune microenvironment and
angiogenesis has been well established, evidence supporting the chemo-free combination of …

Dendritic cells combining with cytokine-induced killer cells synergize chemotherapy in patients with late-stage non-small cell lung cancer

R Zhong, J Teng, B Han, H Zhong - Cancer immunology, immunotherapy, 2011 - Springer
Background Lung cancer is the leading cause for cancer-related mortality and morbidity,
and the survival of late-stage non-small cell lung cancer (NSCLC) remains poor. We hereby …

[HTML][HTML] hsa_circ_0003222 accelerates stemness and progression of non-small cell lung cancer by sponging miR-527

C Li, J Zhang, X Yang, C Hu, T Chu, R Zhong… - Cell death & …, 2021 - nature.com
The relationship between circular RNA (circRNA) and cancer stem cells (CSCs) is uncertain.
We have investigated the combined influence of CSCs, circRNA (hsa_circ_0003222), and …

Role of anlotinib-induced CCL2 decrease in anti-angiogenesis and response prediction for nonsmall cell lung cancer therapy

J Lu, H Zhong, T Chu, X Zhang, R Li… - European …, 2019 - Eur Respiratory Soc
Background Anlotinib has been demonstrated in clinical trials to be effective in prolonging
the progression-free survival (PFS) and overall survival (OS) of refractory advanced nonsmall …

Multi‐target angiogenesis inhibitor combined with PD‐1 inhibitors may benefit advanced non‐small cell lung cancer patients in late line after failure of EGFR‐TKI …

…, H Zhong, B Han, J Xia, R Zhong - … Journal of Cancer, 2023 - Wiley Online Library
Treatments for NSCLC patients with EGFR‐TKI resistance are limited. Given that immunotherapy
and antiangiogenic agents may have synergistic antitumor effects, we aimed to analyze …

Racial differences in characteristics and prognoses between Asian and white patients with nonsmall cell lung cancer receiving atezolizumab: an ancillary analysis of …

…, R Zhong, W Zhang, T Chu, H Zhong… - … Journal of Cancer, 2020 - Wiley Online Library
This study aimed to compare the differences in characteristics and prognoses between Asian
and white patients receiving immunotherapy for nonsmall cell lung cancer (NSCLC). We …

RETRACTED ARTICLE: MMP9 activation triggered by epidermal growth factor induced FoxO1 nuclear exclusion in non-small cell lung cancer

J Pei, Y Lou, R Zhong, B Han - Tumor Biology, 2014 - Springer
The molecular mechanism underlying activation of matrix metallopeptidase 9 (MMP9) in non-small
cell lung cancer (NSCLC) cells, which controls cancer invasiveness and metastasis, …

[HTML][HTML] Tumor-infiltrating CD45RO+ memory cells correlate with favorable prognosis in patients with lung adenocarcinoma

Z Hu, X Gu, R Zhong, H Zhong - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
Background The present study aimed to investigate the association of CD45RO+, CD8+,
CCR7+ and FOXP3+ tumor-infiltrating lymphocytes (TILs) with the clinicopathological features …

Sonographic features of endobronchial ultrasonography predict intrathoracic lymph node metastasis in lung cancer patients

L Wang, W Wu, Y Hu, J Teng, R Zhong, B Han… - The Annals of thoracic …, 2015 - Elsevier
Background Intrathoracic lymph node sampling by endobronchial ultrasonography-guided
transbronchial needle aspiration (EBUS-TBNA) has become a standard of care in staging …

Efficacy and safety of anlotinib combined with PD‐1/PD‐L1 inhibitors as second‐line and subsequent therapy in advanced small‐cell lung cancer

…, J Xu, R Qiao, B Han, H Zhong, R Zhong - Cancer Medicine, 2023 - Wiley Online Library
Objectives Treatments for advanced small‐cell lung cancer (SCLC) patients who are resistant
to first‐line chemotherapy are limited. Given that antiangiogenic agents and immune‐…