Cancer incidence, mortality, and burden in China: a time‐trend analysis and comparison with the United States and United Kingdom based on the global …

H Qiu, S Cao, R Xu - Cancer communications, 2021 - Wiley Online Library
Background Cancer is one of the leading causes of death and a main economic burden in
China. Investigating the differences in cancer patterns and control strategies between China …

Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or …

…, S Luo, Z Li, K Gu, J Lu, J Xu, Q Fan, R Xu… - Cancer …, 2021 - Wiley Online Library
Background Current treatment options for human epidermal growth factor receptor 2 (HER2)‐overexpressing
gastric cancer at third‐line have shown limited clinical benefit. Further, …

Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a …

J Li, S Qin, R Xu, TCC Yau, B Ma, H Pan, J Xu… - The lancet …, 2015 - thelancet.com
Background In the international randomised phase 3 CORRECT trial (NCT01103323),
regorafenib significantly improved overall survival versus placebo in patients with treatment-…

[PDF][PDF] Randomized, double-blind, placebo-controlled phase III trial of apatinib in patients with chemotherapy-refractory advanced or metastatic adenocarcinoma of the …

J Li, S Qin, J Xu, J Xiong, C Wu, Y Bai, W Liu… - Journal of Clinical …, 2016 - mrimedical.net
Purpose There is currently no standard treatment strategy for patients with advanced metastatic
gastric cancer experiencing progression after two or more lines of chemotherapy. We …

[HTML][HTML] Expert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition)

…, B Xing, B Xiong, J Xu, J Xu, N Xu, R Xu, Z Xu… - Journal of hematology & …, 2019 - Springer
The lungs are the second most common site of metastasis for colorectal cancer (CRC) after
the liver. Rectal cancer is associated with a higher incidence of lung metastases compared to …

[HTML][HTML] Current management of chemotherapy-induced neutropenia in adults: key points and new challenges: Committee of neoplastic supportive-care (CONS) …

…, L Xiao, Q Zhang, W Qiu, B Xu, R Xu… - Cancer biology & …, 2020 - ncbi.nlm.nih.gov
Chemotherapy-induced neutropenia (CIN) is a potentially fatal and common complication in
myelosuppressive chemotherapy. The timing and grade of CIN may play prognostic and …

[HTML][HTML] Bevacizumab plus capecitabine and cisplatin in Chinese patients with inoperable locally advanced or metastatic gastric or gastroesophageal junction cancer …

L Shen, J Li, J Xu, H Pan, G Dai, S Qin, L Wang… - Gastric cancer, 2015 - Springer
Background In the AVAGAST study, fluoropyrimidine and cisplatin plus bevacizumab did
not significantly improve overall survival (OS) versus fluoropyrimidine and cisplatin plus …

[HTML][HTML] Pattern of distant metastases in colorectal cancer: a SEER based study

M Qiu, J Hu, D Yang, DP Cosgrove, R Xu - Oncotarget, 2015 - ncbi.nlm.nih.gov
More and more evidences suggest that primary colon and rectum tumors should not be
considered as a single disease entity. In this manuscript, we evaluate the metastatic patterns of …

[PDF][PDF] Results of a randomized, double-blind, placebo-controlled, phase III trial of trifluridine/tipiracil (TAS-102) monotherapy in Asian patients with previously treated …

J Xu, TW Kim, L Shen, V Sriuranpong… - Journal of Clinical …, 2018 - researchgate.net
Purpose Trifluridine/tipiracil (TAS-102) was effective in patients with metastatic colorectal
cancer (mCRC) in a phase II Japanese trial. This regional trial evaluated the efficacy and safety …

Overexpression of GOLPH3 promotes proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor

Z Zeng, H Lin, X Zhao, G Liu, X Wang, R Xu… - Clinical Cancer …, 2012 - AACR
Purpose: Golgi phosphoprotein 3 (GOLPH3) has been reported to be involved in various
biologic processes. The clinical significance and biologic role of GOLPH3 in breast cancer, …