Objective: Features of colorectal cancer such as natural history, molecular, chromosomal,
and epigenetic alterations have been well described. However, there is still a lack of accurate …

Objectives To compare the interobserver variability in the diagnostic of serrated and non-serrated
adenomatous lesions and hyperplastic polyps of colon between two groups of …

Colorectal cancer can develop through molecular, chromosomal, and epigenetic cumulative
changes that transform the normal intestinal epithelium into the colorectal polyps, called …

Objectives: Determine immunohistochemical expression of Phosphatase and tensin
homolog (PTEN), Phosphatidylinositol 3 kinase (PI3K), Cycloxygenase-2 (COX2) and one …

SciELO - Brasil - Do standardization and quantification of histopathological criteria improve
the diagnosis of inflammatory bowel disease? Do standardization and quantification of …

Introduction Anal intraepithelial neoplasia (AIN) is a premalignant lesion of the anal canal
associated with HPV, with a higher prevalence in immunosuppressed individuals. Patients …

SciELO - Brasil - Clinical-pathological and p53 protein expression study in dysplasia
associated with ulcerative colitis Clinical-pathological and p53 protein expression study in …

Laterally spreading tumors (LSTs) are considered a special subtype of superficial colorectal
tumor. This study was performed to characterize the clinicopathological features and …

Germline mutations of the LKB1 gene lead to Peutz–Jeghers syndrome (PJS), which is
associated with a predisposition to gastrointestinal polyposis and cancer. In this study we tested …

Colorectal cancer (CRC) is a heterogeneous disease and a major contributor to world cancer
mortality rates. Molecular subtypes of CRC have become standards for CRC classification …