Purpose To perform a meta-analysis to report pooled estimates for underestimation of
invasive breast cancer (where core-needle biopsy [CNB] shows ductal carcinoma in situ [DCIS] …

Objective: Systematic evidence synthesis of ultrasound-guided needle biopsy (UNB) of axillary
nodes in breast cancer. Summary Background Data: Women affected by invasive breast …

Purpose To investigate the extent of objective ‘non-beneficial treatments (NBTs)’ (too much)
anytime in the last 6 months of life in routine hospital care. Data sources English language …

Rapid urine tests, such as microscopy, for bacteria and white cells, and dipsticks, for leucocyte
esterase and nitrites, are often used in children that are unwell to guide early diagnosis …

Background Although there is no consensus on whether pre-operative MRI in women with
breast cancer (BC) benefits surgical treatment, MRI continues to be used pre-operatively in …

Introduction Seasonal influenza affects millions of people globally each year, causing significant
morbidity and mortality. However, there remains substantial uncertainty about the attack …

Background A quadrivalent influenza vaccine (QIV) includes two A strains (A/H1N1, A/H3N2)
and two B lineages (B/Victoria, B/Yamagata). The presence of both B lineages eliminate …

Background: Central compartment lymph node metastases in papillary thyroid carcinoma (PTC)
are difficult to detect preoperatively, and the role of routine or prophylactic central …

Purpose: To develop more evidence-based guidelines for the frequency of patient follow-up
after treatment of localized (American Joint Committee on Cancer [AJCC] stage I or II) …

Objective To describe the range of decision aids (DAs) available to enable informed choice
for older patients at the end of life and assess their effectiveness or acceptability. Methods …