Nivolumab+ chemotherapy versus chemotherapy as neoadjuvant treatment for resectable stage IIIA NSCLC: Primary endpoint results of pathological complete …
…, R Benitez, C Aguado De La Rosa, R Palmero… - 2022 - ascopubs.org
8501 Background: Non-small cell lung cancer (NSCLC) is incurable in most patients with
locally advanced stage IIIA disease. Previous results indicate that the use of neoadjuvant …
locally advanced stage IIIA disease. Previous results indicate that the use of neoadjuvant …
[HTML][HTML] Perioperative nivolumab and chemotherapy in stage III non–small-cell lung cancer
…, C Aguado de la Rosa, R Palmero… - … England Journal of …, 2023 - Mass Medical Soc
Background Approximately 20% of patients with non–small-cell lung cancer (NSCLC)
receive a diagnosis of stage III disease. There is no current consensus regarding the most …
receive a diagnosis of stage III disease. There is no current consensus regarding the most …
Spatially preserved multi-region transcriptomic subtyping and biomarkers of chemoimmunotherapy outcome in extensive-stage small cell lung cancer
…, C Aguado, V Cebey-Lopez, J Valdivia, R Palmero… - Clinical Cancer …, 2024 - AACR
Background: Transcriptomic subtyping holds promise for personalized therapy in extensive-stage
small-cell lung cancer (ES-SCLC). In this study, we aimed to assess intratumoral …
small-cell lung cancer (ES-SCLC). In this study, we aimed to assess intratumoral …
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a …
…, A Vergnenegre, B Massuti, E Felip, R Palmero… - The lancet …, 2012 - thelancet.com
Background Erlotinib has been shown to improve progression-free survival compared with
chemotherapy when given as first-line treatment for Asian patients with non-small-cell lung …
chemotherapy when given as first-line treatment for Asian patients with non-small-cell lung …
[HTML][HTML] Screening for epidermal growth factor receptor mutations in lung cancer
Background Activating mutations in the epidermal growth factor receptor gene (EGFR)
confer hypersensitivity to the tyrosine kinase inhibitors gefitinib and erlotinib in patients with …
confer hypersensitivity to the tyrosine kinase inhibitors gefitinib and erlotinib in patients with …
Thyroid dysfunction induced by nivolumab: searching for disease patterns and outcomes
I Peiró, R Palmero, P Iglesias, JJ Díez, A Simó-Servat… - Endocrine, 2019 - Springer
Purpose Nivolumab is a monoclonal antibody that blocks the activation of programmed
death-1 receptor, promoting T-cell activation against cancer cells. Thyroid dysfunction (TD) is a …
death-1 receptor, promoting T-cell activation against cancer cells. Thyroid dysfunction (TD) is a …
Erlotinib and bevacizumab in patients with advanced non-small-cell lung cancer and activating EGFR mutations (BELIEF): an international, multicentre, single-arm …
…, O Gautschi, S Peters, B Massutí, R Palmero… - The Lancet …, 2017 - thelancet.com
Background The tyrosine kinase inhibitor erlotinib improves the outcomes of patients with
advanced non-small-cell lung carcinoma (NSCLC) harbouring epidermal growth factor …
advanced non-small-cell lung carcinoma (NSCLC) harbouring epidermal growth factor …
[HTML][HTML] Geriatric assessment may help decision-making in elderly patients with inoperable, locally advanced non-small-cell lung cancer
…, J Saldaña, J Linares, JC Ruffinelli, R Palmero… - British journal of …, 2018 - nature.com
Background: Although concurrent chemoradiotherapy (cCRT) increases survival in patients
with inoperable, locally advanced non-small-cell lung cancer (NSCLC), there is no …
with inoperable, locally advanced non-small-cell lung cancer (NSCLC), there is no …
Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis
…, M Varela, JC Ruffinelli, R Palmero… - The Lancet …, 2018 - thelancet.com
Background Anti-programmed death-1 (PD-1) treatment for advanced non-small-cell lung
cancer (NSCLC) has improved the survival of patients. However, a substantial percentage of …
cancer (NSCLC) has improved the survival of patients. However, a substantial percentage of …
Encephalitis induced by immune checkpoint inhibitors: a systematic review
…, M Simó, N Vilariño, M Alemany, R Palmero… - JAMA …, 2021 - jamanetwork.com
Importance Encephalitis is a severe immune-related adverse event secondary to treatment
with immune checkpoint inhibitors (ICIs). The spectrum of ICI-induced encephalitis (ICI-iE) …
with immune checkpoint inhibitors (ICIs). The spectrum of ICI-induced encephalitis (ICI-iE) …