Nivolumab+ chemotherapy versus chemotherapy as neoadjuvant treatment for resectable stage IIIA NSCLC: Primary endpoint results of pathological complete …

…, R Benitez, C Aguado De La Rosa, R Palmero… - 2022 - ascopubs.org
8501 Background: Non-small cell lung cancer (NSCLC) is incurable in most patients with
locally advanced stage IIIA disease. Previous results indicate that the use of neoadjuvant …

[HTML][HTML] Perioperative nivolumab and chemotherapy in stage III non–small-cell lung cancer

…, C Aguado de la Rosa, R Palmero… - … England Journal of …, 2023 - Mass Medical Soc
Background Approximately 20% of patients with non–small-cell lung cancer (NSCLC)
receive a diagnosis of stage III disease. There is no current consensus regarding the most …

Spatially preserved multi-region transcriptomic subtyping and biomarkers of chemoimmunotherapy outcome in extensive-stage small cell lung cancer

…, C Aguado, V Cebey-Lopez, J Valdivia, R Palmero… - Clinical Cancer …, 2024 - AACR
Background: Transcriptomic subtyping holds promise for personalized therapy in extensive-stage
small-cell lung cancer (ES-SCLC). In this study, we aimed to assess intratumoral …

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a …

…, A Vergnenegre, B Massuti, E Felip, R Palmero… - The lancet …, 2012 - thelancet.com
Background Erlotinib has been shown to improve progression-free survival compared with
chemotherapy when given as first-line treatment for Asian patients with non-small-cell lung …

[HTML][HTML] Screening for epidermal growth factor receptor mutations in lung cancer

…, S Catot, C Rolfo, N Reguart, R Palmero… - … England Journal of …, 2009 - Mass Medical Soc
Background Activating mutations in the epidermal growth factor receptor gene (EGFR)
confer hypersensitivity to the tyrosine kinase inhibitors gefitinib and erlotinib in patients with …

Thyroid dysfunction induced by nivolumab: searching for disease patterns and outcomes

I Peiró, R Palmero, P Iglesias, JJ Díez, A Simó-Servat… - Endocrine, 2019 - Springer
Purpose Nivolumab is a monoclonal antibody that blocks the activation of programmed
death-1 receptor, promoting T-cell activation against cancer cells. Thyroid dysfunction (TD) is a …

Erlotinib and bevacizumab in patients with advanced non-small-cell lung cancer and activating EGFR mutations (BELIEF): an international, multicentre, single-arm …

…, O Gautschi, S Peters, B Massutí, R Palmero… - The Lancet …, 2017 - thelancet.com
Background The tyrosine kinase inhibitor erlotinib improves the outcomes of patients with
advanced non-small-cell lung carcinoma (NSCLC) harbouring epidermal growth factor …

[HTML][HTML] Geriatric assessment may help decision-making in elderly patients with inoperable, locally advanced non-small-cell lung cancer

…, J Saldaña, J Linares, JC Ruffinelli, R Palmero… - British journal of …, 2018 - nature.com
Background: Although concurrent chemoradiotherapy (cCRT) increases survival in patients
with inoperable, locally advanced non-small-cell lung cancer (NSCLC), there is no …

Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis

…, M Varela, JC Ruffinelli, R Palmero… - The Lancet …, 2018 - thelancet.com
Background Anti-programmed death-1 (PD-1) treatment for advanced non-small-cell lung
cancer (NSCLC) has improved the survival of patients. However, a substantial percentage of …

Encephalitis induced by immune checkpoint inhibitors: a systematic review

…, M Simó, N Vilariño, M Alemany, R Palmero… - JAMA …, 2021 - jamanetwork.com
Importance Encephalitis is a severe immune-related adverse event secondary to treatment
with immune checkpoint inhibitors (ICIs). The spectrum of ICI-induced encephalitis (ICI-iE) …